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一家区综合医院中疑似感染性心内膜炎患者的蛛网膜下腔出血:基于病例报告的文献综述

Subarachnoid Haemorrhage in a Patient With Suspected Infective Endocarditis in a District General Hospital: A Case Report-Based Literature Review.

作者信息

Khan Zahid, Warrier Vinod, Muhammad SyedAun, Mckechnie Charlie

机构信息

Cardiology, Royal Free Hospital, London, GBR.

Internal Medicine, Mid and South Essex NHS Foundation Trust, Southend on Sea, GBR.

出版信息

Cureus. 2022 Jan 25;14(1):e21602. doi: 10.7759/cureus.21602. eCollection 2022 Jan.

Abstract

We describe the case of a 70-year-old lady who presented to a district general hospital during an evening with fevers, feeling generally unwell. She was found to have weakness in her left upper limb and went on to have tonic-clonic seizures whilst in the Accident and Emergency Department. CT scan of the brain showed subarachnoid haemorrhage, in absence of headache, in the right frontal, superior parietal and left occipital regions. Her C-reactive protein level was elevated at 426 mg/L and her urine dip was normal. Chest radiograph showed small bilateral pleural effusions. In addition to the above-mentioned findings on clinical examination, she also had pansystolic murmur although did not have any other feature of infective endocarditis (IE). In view of the above findings, normal chest examination and no urinary symptoms, the decision was made to treat this as a case of IE empirically. She subsequently went into fast atrial fibrillation requiring direct current (DC) cardioversion and intensive care unit admission due to hypotension. The next day, echocardiography confirmed vegetations and blood cultures were positive for . Her MRI scan of the brain confirmed parenchymal haemorrhages and haemorrhagic infarcts. She completed a 6-week course of antibiotics and clinically improved. Despite being critically unwell, appropriate antibiotics were initiated within hours of her admission in view of clinical suspicion of underlying IE, which aided her recovery.

摘要

我们描述了一位70岁女性的病例,她在晚上因发热前往一家地区综合医院就诊,感觉全身不适。她被发现左上肢无力,在急诊部时继而出现强直阵挛性发作。脑部CT扫描显示蛛网膜下腔出血,位于右侧额叶、顶叶上部和左侧枕叶区域,且无头痛症状。她的C反应蛋白水平升高至426mg/L,尿液试纸检测正常。胸部X线片显示双侧少量胸腔积液。除了上述临床检查结果外,她还存在全收缩期杂音,尽管没有感染性心内膜炎(IE)的任何其他特征。鉴于上述发现、胸部检查正常且无泌尿系统症状,决定将此病例按IE进行经验性治疗。她随后出现快速房颤,因低血压需要直流电(DC)复律并入住重症监护病房。第二天,超声心动图证实有赘生物,血培养结果为阳性。她的脑部MRI扫描证实存在实质出血和出血性梗死。她完成了为期6周的抗生素疗程,临床症状有所改善。尽管病情严重,但鉴于临床怀疑潜在的IE,在她入院数小时内就开始使用了适当的抗生素,这有助于她的康复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2c6/8873461/9c1ad6669ee3/cureus-0014-00000021602-i01.jpg

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