Concerns over functional experiments, interpretation, and required controls. Reply.
作者信息
Hsieh Wan-Chen, Chen Shih-Yu
机构信息
Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Genome and Systems Biology Degree Program, National Taiwan University, Taipei, Taiwan.
出版信息
J Clin Invest. 2022 Mar 1;132(5). doi: 10.1172/JCI158155.
Abstract
摘要
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Concerns over functional experiments, interpretation, and required controls. Reply.对功能实验、解释及所需对照的担忧。回复。
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本文引用的文献
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ACE2-Independent Interaction of SARS-CoV-2 Spike Protein with Human Epithelial Cells Is Inhibited by Unfractionated Heparin.SARS-CoV-2 刺突蛋白与人类上皮细胞的非依赖性相互作用被未分级肝素抑制。
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SARS-CoV-2 Spike Protein Induces Paracrine Senescence and Leukocyte Adhesion in Endothelial Cells.SARS-CoV-2 刺突蛋白诱导内皮细胞旁分泌衰老和白细胞黏附。
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SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells.SARS-CoV-2 刺突蛋白通过激活上皮细胞中的血管紧张素 II 受体信号促进 IL-6 转信号。
PLoS Pathog. 2020 Dec 7;16(12):e1009128. doi: 10.1371/journal.ppat.1009128. eCollection 2020 Dec.
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SARS-CoV-2 spike protein-mediated cell signaling in lung vascular cells.SARS-CoV-2 刺突蛋白介导的肺血管细胞中的细胞信号转导。
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