Immunology Frontier Research Center (IFReC), Osaka University, 3-3-1, Yamada-oka, Suita 565-0871, Japan.
Int Immunol. 2021 Sep 25;33(10):507-513. doi: 10.1093/intimm/dxab008.
Understanding the precise nature and durability of protective immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential in order to gain insight into the pathophysiology of coronavirus disease 2019 (COVID-19) and to develop novel treatment strategies to this disease. Here, I succinctly summarize what is currently known and unknown about the immune response during COVID-19 and discuss whether natural infections can lead to herd immunity.
了解针对严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）的保护性免疫的确切性质和持久性对于深入了解 2019 年冠状病毒病（COVID-19）的病理生理学以及开发针对这种疾病的新型治疗策略至关重要。在这里，我简明扼要地总结了目前已知和未知的 COVID-19 期间的免疫反应，并讨论了自然感染是否可以导致群体免疫。
