Kohnle W, Vanek E, Federlin K, Franz H E
Dtsch Med Wochenschr. 1975 Dec 19;100(51):2598-602. doi: 10.1055/s-0028-1106592.
The immunofluorescence test for demonstrating antibody-coated bacteria as a direct method of localizing urinary-tract infection was performed on 34 patients, results being compared with the Fairley test. Mid-stream urine contained at least 10(5) bacteria/ml in all patients. The direct localization method revealed upper urinary-tract infection (renal bacteriuria) in 18 patients, lower urinary-tract infection (cystitis) in eight. Presence of antibody-coated bacteria correlated well with renal bacteriuria, such antibody having been demonstrated in all of the eighteen patients with renal bacteriuria but in none of the eight with lower urinary-tract infection (cause located in the bladder). The test has proved to be highly sensitive method for differentiating between upper and lower urinary-tract infection.
对34例患者进行了免疫荧光试验,以作为定位尿路感染的直接方法来显示抗体包被细菌,结果与费尔利试验进行了比较。所有患者的中段尿中细菌含量至少为10⁵/ml。直接定位法显示18例患者为上尿路感染(肾菌尿),8例为下尿路感染(膀胱炎)。抗体包被细菌的存在与肾菌尿密切相关,在18例肾菌尿患者中均检测到此类抗体,而8例下尿路感染(病因位于膀胱)患者中均未检测到。该试验已被证明是区分上、下尿路感染的高度敏感方法。