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透明边缘角膜变性

Pellucid marginal corneal degeneration.

作者信息

Krachmer J H

出版信息

Arch Ophthalmol. 1978 Jul;96(7):1217-21. doi: 10.1001/archopht.1978.03910060051009.

DOI:10.1001/archopht.1978.03910060051009
PMID:352310
Abstract

Pellucid marginal degeneration of the cornea is a bilateral, clear, inferior, peripheral corneal-thinning disorder. Protrusion of the cornea occurs above a band of thinning, which is located 1 to 2 mm from the limbus and measures 1 to 2 mm in width. American ophthalmologists are generally not familiar with the condition because most of the literature concerning pellucid degeneration is European. Four cases are described. This condition is differentiated from other noninflammatory cornel-thinning disorders such as keratoconus, keratoglobus, keratotorus, and posterior keratoconus. It is also differentiated from peripheral corneal disorders associated with inflammation such as Terrien's peripheral corneal degeneration, Mooren's ulcers, and ulcers from connective tissue disease.

摘要

角膜透明边缘变性是一种双侧性、透明的、下方周边角膜变薄病症。角膜膨出发生在一条变薄带上方,该变薄带位于距角膜缘1至2毫米处,宽度为1至2毫米。美国眼科医生通常不熟悉这种病症,因为大多数关于透明变性的文献来自欧洲。本文描述了4例病例。这种病症与其他非炎性角膜变薄病症相鉴别,如圆锥角膜、球形角膜、角膜隆凸和后圆锥角膜。它也与伴有炎症的周边角膜病症相鉴别,如泰里恩周边角膜变性、莫伦溃疡以及结缔组织病引起的溃疡。

相似文献

1
Pellucid marginal corneal degeneration.透明边缘角膜变性
Arch Ophthalmol. 1978 Jul;96(7):1217-21. doi: 10.1001/archopht.1978.03910060051009.
2
Keratoconus and related noninflammatory corneal thinning disorders.圆锥角膜及相关非炎性角膜变薄疾病
Surv Ophthalmol. 1984 Jan-Feb;28(4):293-322. doi: 10.1016/0039-6257(84)90094-8.
3
Acute corneal edema in pellucid marginal degeneration or acute marginal keratoconus.透明边缘变性或急性边缘圆锥角膜中的急性角膜水肿。
Cornea. 1987;6(3):169-74. doi: 10.1097/00003226-198706030-00003.
4
Pellucid marginal degeneration: Detection, discrimination from other corneal ectatic disorders and progression.先天性边缘性角膜营养不良:检测、与其他角膜扩张性疾病的鉴别诊断及进展。
Cont Lens Anterior Eye. 2019 Aug;42(4):341-349. doi: 10.1016/j.clae.2018.11.010. Epub 2018 Nov 22.
5
[A severe unilateral corneal ectasia in children].[儿童严重单侧角膜扩张症]
J Fr Ophtalmol. 2023 Dec;46(10):1244-1246. doi: 10.1016/j.jfo.2023.05.033. Epub 2023 Nov 17.
6
Terrien's marginal degeneration: corneal topography.泰里恩边缘性角膜变性:角膜地形图
Refract Corneal Surg. 1990 Jan-Feb;6(1):15-20.
7
[Acute spontaneous corneal hydrops in a patient with pellucid marginal corneal degeneration].
J Fr Ophtalmol. 2006 Jun;29(6):e13. doi: 10.1016/s0181-5512(06)73830-x.
8
Topographic analysis in pellucid marginal corneal degeneration and keratoglobus.透明边缘性角膜变性和球形角膜的地形分析
Eye (Lond). 1996;10 ( Pt 4):451-5. doi: 10.1038/eye.1996.99.
9
Central cornea involvement in Terrien's degeneration.
Ophthalmic Surg. 1983 Mar;14(3):245-7.
10
Pellucid marginal corneal degeneration.透明边缘角膜变性
Ophthalmology. 2004 Jun;111(6):1102-7. doi: 10.1016/j.ophtha.2003.09.035.

引用本文的文献

1
Pellucid Marginal Degeneration: A Comprehensive Review of Pathophysiology, Diagnosis, and Management Strategies.透明边缘变性:病理生理学、诊断及管理策略的全面综述
J Clin Med. 2025 Jul 22;14(15):5178. doi: 10.3390/jcm14155178.
2
Overview of Corneal Transplantation for the Nonophthalmologist.非眼科医生的角膜移植概述
Transplant Direct. 2023 Jan 12;9(2):e1434. doi: 10.1097/TXD.0000000000001434. eCollection 2023 Feb.
3
Corneal Cross-Linking in Pellucid Marginal Degeneration: Evaluation after Five Years.透明边缘变性的角膜交联:五年后的评估
J Curr Ophthalmol. 2022 Jul 26;34(2):229-233. doi: 10.4103/joco.joco_16_22. eCollection 2022 Apr-Jun.
4
Demographic, clinical and tomographic characteristics of pellucid marginal degeneration patients in South Egyptian population.南埃及人群中透明边缘性脉络膜变性患者的人口学、临床和影像学特征。
Int Ophthalmol. 2022 Oct;42(10):3237-3242. doi: 10.1007/s10792-022-02326-1. Epub 2022 Aug 24.
5
Pellucid marginal corneal degeneration in a teenager.青少年的边缘性角膜透亮变性
BMJ Case Rep. 2022 Aug 19;15(8):e248599. doi: 10.1136/bcr-2021-248599.
6
Clinical profile and demographic distribution of pellucid marginal corneal degeneration in India: A study of 559 patients.印度透明边缘角膜变性的临床特征与人口统计学分布:一项对559例患者的研究
Indian J Ophthalmol. 2021 Dec;69(12):3488-3493. doi: 10.4103/ijo.IJO_553_21.
7
Utility of distant indirect ophthalmoscopy as screening tool in a case of pellucid marginal degeneration.间接检眼镜作为透明边缘变性病例筛查工具的效用。
BMJ Case Rep. 2020 Sep 9;13(9):e238787. doi: 10.1136/bcr-2020-238787.
8
Corneal hysteresis and corneal resistance factor in pellucid marginal corneal degeneration.透明边缘性角膜变性中的角膜滞后和角膜阻力因子。
J Curr Ophthalmol. 2018 Feb 3;30(2):187. doi: 10.1016/j.joco.2017.12.002. eCollection 2018 Jun.
9
Acute hydrops with a 180-degree massive edematous cavern demonstrated by three dimensional view of anterior segment optical coherence tomography in a patient with pellucid marginal corneal degeneration, a case report.一例透明边缘角膜变性患者眼前节光学相干断层扫描三维视图显示急性积液伴180度巨大水肿性腔隙,病例报告
BMC Ophthalmol. 2018 Apr 13;18(1):92. doi: 10.1186/s12886-018-0757-7.
10
Corneal hysteresis and corneal resistance factor in pellucid marginal degeneration.透明边缘变性中的角膜滞后和角膜阻力因子。
J Curr Ophthalmol. 2017 Aug 18;30(1):42-47. doi: 10.1016/j.joco.2017.08.002. eCollection 2018 Mar.