Chaicumpa V, Jenkin C R
Aust J Exp Biol Med Sci. 1978 Feb;56(1):61-8. doi: 10.1038/icb.1978.7.
The results of the present study show that peritoneal exudate cells from mice immune to infection with Nematospiroides dubius are able in vitro to damage the third stage infective larvae as measured by a loss in infectivity. The ability of these cells to function in the absence of specific antibody seems to be related to the presence of trypsin labile factors on their surfaces. Lymphocytes from immune mice are also able to damage the larvae. The suggestion is made that 'activated' macrophages may play an important role in immunity to this infection.
本研究结果表明，对杜氏丝状线虫感染产生免疫的小鼠腹腔渗出细胞，在体外能够通过感染力丧失来损伤第三期感染性幼虫。这些细胞在没有特异性抗体的情况下发挥功能的能力，似乎与其表面存在对胰蛋白酶不稳定的因子有关。来自免疫小鼠的淋巴细胞也能够损伤幼虫。有人提出，“活化的”巨噬细胞可能在针对这种感染的免疫中发挥重要作用。
