McDonald Christine F
Austin Health, Melbourne.
Faculty of Medicine, University of Melbourne.
Aust Prescr. 2022 Feb;45(1):21-24. doi: 10.18773/austprescr.2022.007. Epub 2022 Feb 1.
Long-term home oxygen therapy improves survival in patients with chronic obstructive pulmonary disease and persistent, severe hypoxaemia. It is uncertain that this benefit extends to patients with other chronic lung diseases. Oxygen is a treatment for hypoxaemia, not breathlessness. To confirm hypoxaemia, blood gas analysis is recommended before prescribing oxygen. There is limited and conflicting evidence that portable oxygen for exertional use is of benefit to patients with chronic obstructive pulmonary disease who do not have severe hypoxaemia. Laboratory studies show improvements in exercise capacity and dyspnoea, but these do not translate into significant benefits in the home setting. Patients should be educated regarding the expected benefits, risks and burdens of home oxygen therapy. It is particularly important that the patient does not smoke.
长期家庭氧疗可提高慢性阻塞性肺疾病和持续性严重低氧血症患者的生存率。这种益处是否能扩展到其他慢性肺部疾病患者尚不确定。氧气是用于治疗低氧血症的，而非治疗呼吸困难。为确认低氧血症，建议在开具氧气处方前进行血气分析。对于没有严重低氧血症的慢性阻塞性肺疾病患者，关于运动时使用便携式氧气是否有益，证据有限且相互矛盾。实验室研究表明运动能力和呼吸困难有所改善，但在家庭环境中并未转化为显著益处。应向患者介绍家庭氧疗的预期益处、风险和负担。特别重要的是患者不要吸烟。
