Waterhouse J C, Howard P
Thorax. 1983 Apr;38(4):302-6. doi: 10.1136/thx.38.4.302.
Breathlessness was measured in 20 patients with severe chronic obstructive lung disease by the use of a visual-analogue scale. Severe resting arterial hypoxaemia was not a feature. The severity of breathlessness measured in this way did not correlate well with the results of spirometric tests or with walking ability. The use of portable oxygen was studied during simple walking tests for its effect on walking ability and the sensation of breathlessness. Portable oxygen improved exercise capacity but a placebo effect of the system probably accounted for some of the improvement. A clear improvement of distressing breathlessness was observed and represented a useful therapeutic response. Breathlessness and simple exercise ability were shown to respond independently to oxygen breathing. The value of short-term intermittent oxygen in patients with severe chronic obstructive lung disease needs to be evaluated in terms of both exercise ability and breathlessness.
采用视觉模拟量表对20例重度慢性阻塞性肺疾病患者的呼吸困难情况进行了测量。患者不存在严重的静息性动脉血氧不足。通过这种方式测得的呼吸困难严重程度与肺量计测试结果或步行能力的相关性不佳。在简单步行测试期间研究了便携式氧气对步行能力和呼吸困难感觉的影响。便携式氧气改善了运动能力，但该系统的安慰剂效应可能在一定程度上促成了这种改善。观察到令人痛苦的呼吸困难有明显改善，这代表了一种有效的治疗反应。结果表明，呼吸困难和简单运动能力对吸氧的反应相互独立。重度慢性阻塞性肺疾病患者短期间歇性吸氧的价值需要从运动能力和呼吸困难两方面进行评估。
