School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
Shandong Provincial Third Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
J Clin Pharm Ther. 2022 Jul;47(7):995-1001. doi: 10.1111/jcpt.13634. Epub 2022 Mar 2.
This study aimed to explore methods to optimize the function of Drug and Therapeutics Committees (DTCs) in controlling irrational drug use. Clinical pharmacologists contribute their specific knowledge and skills to DTCs and help guide rational therapeutics. The DTC is the highest organization of hospital pharmacy management.
From January 2016 to August 2021, the DTC promoted the optimization of clinical drug treatment schemes and reduced unreasonable drug use by improving the organizational framework, clarifying the division of functions, regularly monitoring drug use, organizing expert comments, scientific decision-making and functional intervention. During this time, we statistically analysed typical management cases, irrational drug use and drug cost to evaluate the effectiveness of the DTC's management.
The DTC's intervention led to a significant reduction in prescribing errors (65.98%, p < 0.05); the intervention acceptance rate increased by 16.37%; and the rate of problem resolution increased by 45.84% (p < 0.05). The level of drug treatment was improved, and the proportion of patients' drug expenses was reduced.
The DTC carried out a series of continuous improvement work that played a significant normative role in clinical drug use. Giving more power to the DTCs can significantly improve the level of drug treatment and reduce unreasonable drug use, which reduces unnecessary drug expenses.
本研究旨在探讨优化药物治疗委员会(DTC)控制不合理用药功能的方法。临床药理学家为 DTC 贡献其特定的知识和技能,帮助指导合理治疗。DTC 是医院药学管理的最高组织。
2016 年 1 月至 2021 年 8 月,DTC 通过改进组织框架、明确职能分工、定期监测用药、组织专家点评、科学决策和功能干预,促进优化临床药物治疗方案,减少不合理用药。在此期间,我们对典型管理案例、不合理用药和药物成本进行了统计分析,以评估 DTC 管理的效果。
DTC 的干预导致处方错误显著减少(65.98%,p<0.05);干预接受率提高了 16.37%;问题解决率提高了 45.84%(p<0.05)。药物治疗水平提高,患者药物费用比例降低。
DTC 开展了一系列持续改进工作,对临床用药起到了显著的规范作用。赋予 DTC 更多权力,可以显著提高药物治疗水平,减少不合理用药,降低不必要的药物费用。