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澳大利亚的药物与治疗委员会:预期表现与实际表现

Drug and Therapeutics Committees in Australia: expected and actual performance.

作者信息

Weekes L M, Brooks C

机构信息

New South Wales Therapeutic Assessment Group Inc, Sydney, Australia.

出版信息

Br J Clin Pharmacol. 1996 Nov;42(5):551-7. doi: 10.1111/j.1365-2125.1996.tb00048.x.

Abstract
  1. This study describes stakeholders' opinions on Drug and Therapeutics Committees (DTCs) and measures the composition, activities and perceived effectiveness of DTCs in Australia. 2. Focus groups explored the opinions of clinicians, consumers and administrators on the goals, objectives and strategies of DTCs. 3. A national survey was sent to 306 hospitals to collect data on the composition, committee processes, goals, objectives, educational activities, policies and decision making of DTCs. 4. Stakeholders believed the DTC should optimise therapeutic health outcomes for patients and economic outcomes for the hospital. Important objectives were availability of safe, efficacious and cost-effective medicines, affordability of medicines and quality use of medicines. 5. The national survey of DTCs found that over 92% of respondents had a DTC in their hospital. Composition was generally representational and most commonly included members from the disciplines of internal medicine, pharmacy and nursing. More than half the DTCs had executive authority although only 21% had an appeals mechanism. 6. The most commonly cited issues for DTCs in 1994-95 were quality drug use, drug policies and spending on high cost drugs. 7. While access to clinical pharmacologists and specialist drug utilisation evaluation (DUE) pharmacists was poor, 71% of DTCs had access to DUE data of some sort. Guidelines (61%), prescribing restrictions (60%) and pharmacist monitoring (63%) were the most commonly used strategies to implement DTC policies and decisions. Audit-feedback activities (61%) and drug bulletins (56%) were the most commonly used interventions. 8. Available information for formulary decision making varied with small rural hospitals having access to significantly less information. The most commonly used information was availability of a therapeutic alternative (87%), efficacy (83%), cost (80%) and estimated usage (78%). 9. On average DTCs reported an ability to implement 75% of decisions (range 0-95%) with teaching hospitals perceived to perform better than other hospital types. 10. This study reveals a high level of expectation for DTC activities and achievements. In Australia DTCs were involved in policy, education and management initiatives to promote best practice in therapeutics. Few committees appeared to have adequate resources to extend services to their wider community.
摘要
  1. 本研究描述了利益相关者对药物与治疗委员会(DTCs)的看法,并衡量了澳大利亚DTCs的组成、活动及感知到的有效性。2. 焦点小组探讨了临床医生、消费者和管理人员对DTCs的目标、目的和策略的看法。3. 向306家医院发送了一项全国性调查,以收集有关DTCs的组成、委员会流程、目标、目的、教育活动、政策和决策的数据。4. 利益相关者认为,DTC应该为患者优化治疗健康结果,并为医院优化经济结果。重要目标包括提供安全、有效且具有成本效益的药物、药物的可负担性以及药物的合理使用。5. 对DTCs的全国性调查发现,超过92%的受访者所在医院设有DTC。其组成通常具有代表性,最常见的成员包括内科、药学和护理领域的人员。超过一半的DTC拥有执行权,尽管只有21%设有上诉机制。6. 1994 - 1995年DTCs最常被提及的问题是药物的合理使用、药物政策以及高成本药物的支出。7. 虽然临床药理学家和专科药物利用评估(DUE)药师的可及性较差,但71%的DTC能够获取某种形式的DUE数据。指南(61%)、处方限制(60%)和药师监测(63%)是实施DTC政策和决策最常用的策略。审核反馈活动(61%)和药物通报(56%)是最常用的干预措施。8. 用于处方集决策的可用信息各不相同,小型农村医院获取的信息明显较少。最常用的信息是是否有治疗替代方案(87%)、疗效(83%)、成本(80%)和估计用量(78%)。9. 平均而言,DTCs报告称能够执行75%的决策(范围为0 - 95%),教学医院被认为比其他类型的医院表现更好。10. 本研究揭示了对DTC活动和成果的高度期望。在澳大利亚,DTC参与了政策、教育和管理举措,以促进治疗方面的最佳实践。似乎很少有委员会拥有足够的资源将服务扩展到更广泛的社区。

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