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评估血小板作用、计数和指标在不同类型实体恶性肿瘤实验室诊断中的预后价值。

Prognostic Value of Evaluating Platelet Role, Count and Indices in Laboratory Diagnosis of Different Types of Solid Malignancies.

出版信息

Pak J Biol Sci. 2022 Jan;25(2):100-105. doi: 10.3923/pjbs.2022.100.105.

DOI:10.3923/pjbs.2022.100.105
PMID:35233997
Abstract

Platelets are associated with the processes that aid in tumour growth and progression. Platelet Count (PLT) and platelet indices like Mean Platelet Volume (MPV), Platelet Large Cell Ratio (P-LCR), Plateletcrit (PCT) and Platelet Distribution Width (PDW) are markers that are linked with platelet activities in cancer. This review involves the evaluation of PLT, MPV and PCT in different cancers. Platelets actions should be always monitored during several diseases, as their potential exceeds the classical function in preventing bleeding. Vast roles of platelets were discovered in several biological functions. Therefore, studying their indices can be effective in the diagnosis of several disorders including cancer.

摘要

血小板与促进肿瘤生长和进展的过程有关。血小板计数 (PLT) 和血小板指数,如平均血小板体积 (MPV)、大血小板比率 (P-LCR)、血小板压积 (PCT) 和血小板分布宽度 (PDW),是与癌症中血小板活性相关的标志物。本综述涉及不同癌症中 PLT、MPV 和 PCT 的评估。在多种疾病中,应始终监测血小板的作用,因为它们的潜在作用超过了预防出血的经典功能。血小板在多种生物学功能中发挥了巨大作用。因此,研究它们的指标可以有效地诊断包括癌症在内的多种疾病。

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