School of Medicine, College of Medicine and Health Sciences, Dire Dawa University, Dire Dawa, Ethiopia.
Department of Public Health, College of Medicine and Health Sciences, Dire Dawa University, Dire Dawa, Ethiopia.
PLoS One. 2022 Mar 2;17(3):e0264461. doi: 10.1371/journal.pone.0264461. eCollection 2022.
Globally, the burden of overweight and obesity is a major cardiovascular disease risk factor and is even higher among patients with psychiatric disorders compared to the general population. This is mainly due to the deleterious lifestyles characterized by physical inactivity, excessive substance use, and unhealthy diets common among patients with psychiatric disorders, as well as the negative metabolic effects of psychotropic medications. Despite these conditions being a high burden among patients with psychiatric illness, little attention is given to them during routine reviews in psychiatric clinics in most African nations, including Ethiopia. Therefore, this study aimed to estimate and compare the prevalence of and associated risk factors for overweight and obesity among patients with psychiatric illnesses.
A comparative cross-sectional study was conducted between severely ill psychiatric patients and non-psychiatric patients in Dire Dawa, Eastern Ethiopia. The study included 192 study participants (96 psychiatric patients and 96 non-psychiatric controls). Weight and height were measured for 192 study participants. Baseline demographic and clinical characteristics of psychiatric and non-psychiatric patients were described. The data were cleaned and analyzed using the Statistical Package for Social Sciences, Version 21. The intergroup comparisons were performed using an independent sample t-test and Chi-square tests. Logistic regression analysis was used to identify the association between overweight/obesity and the associated variables.
The magnitude of overweight/obesity was significantly higher in the severely ill psychiatric groups (43.8%) than in the non-exposed controls (20.80%). The prevalence of overweight/obesity was highest in major depressive disorders (40%), followed by schizophrenia (32%), and bipolar disorder (28%).
There was a high prevalence of obesity/overweight among psychiatric patients. Educational status, unemployment, and late stages of the disease were significant predictors of overweight/ obesity. Clinicians should be aware of the health consequences of overweight/obesity, and considering screening strategies as a part of routine psychiatric care is strongly recommended.
在全球范围内,超重和肥胖是心血管疾病的主要危险因素,在精神疾病患者中比普通人群更高。这主要是由于精神疾病患者生活方式不健康,身体活动不足、过度使用物质和不健康饮食,以及精神药物的代谢负面影响。尽管这些情况在精神疾病患者中负担沉重,但在大多数非洲国家,包括埃塞俄比亚,在精神科诊所的常规检查中很少关注这些情况。因此,本研究旨在评估和比较精神疾病患者超重和肥胖的患病率和相关危险因素。
在埃塞俄比亚东部的 Dire Dawa 市,对严重精神疾病患者和非精神疾病患者进行了一项比较性横断面研究。研究包括 192 名研究参与者(96 名精神疾病患者和 96 名非精神疾病对照者)。对 192 名研究参与者的体重和身高进行了测量。描述了精神和非精神疾病患者的基线人口统计学和临床特征。使用社会科学统计软件包(SPSS)版本 21 对数据进行清理和分析。使用独立样本 t 检验和卡方检验进行组间比较。使用逻辑回归分析来确定超重/肥胖与相关变量之间的关联。
严重精神疾病组(43.8%)的超重/肥胖程度明显高于未暴露对照组(20.80%)。超重/肥胖的患病率在重度抑郁症中最高(40%),其次是精神分裂症(32%)和双相情感障碍(28%)。
精神疾病患者中肥胖/超重的患病率很高。教育程度、失业和疾病晚期是超重/肥胖的重要预测因素。临床医生应意识到超重/肥胖的健康后果,并强烈建议将筛查策略作为常规精神保健的一部分。