Cheng Qiong, Zhang Feng, Tian Tixian, Wu Lan, Li Linna, Chen Meixia, Zhou Ye
Department of Ophthalmology, Taikang Tongji (Wuhan) Hospital, Sixin Road North, Wuhan 430050, China.
Key Laboratory of Metallurgical Equipment and Control Technology, Ministry of Education, Wuhan University of Science and Technology, Wuhan 430081, China.
J Healthc Eng. 2022 Feb 21;2022:4682901. doi: 10.1155/2022/4682901. eCollection 2022.
Cone-shaped corneas are blinding eye diseases characterised by dilated and thinning corneal tissue and forward conical protrusions, most often in adolescents. Early detection and intervention can prevent further dilatation of the cornea. The prevailing examination methods and techniques are not difficult to diagnose clinical cone corneas, but there are limitations in the diagnosis of early cone corneas (static cone corneas and subclinical cone corneas). In this study, we investigated the diagnostic value of the combination of these two instruments in the diagnosis of clinical cone corneas and subclinical cone corneas by performing the Pentacam and Corvis ST examinations in healthy eyes and dystrophic cone corneas. This study provides a theoretical basis for early cone cornea screening and diagnosis. The analysis revealed that only TP, SPA1, ARTh, and bIOP were normally distributed among all included parameters, and only bIOP was normally distributed with equal variance. TBI and CBI indices have a certain sensitivity and specificity for the diagnosis of subclinical cone corneas, with a strong diagnostic ability, and can be used for screening and early diagnosis of cone corneas.
圆锥角膜是一种致盲性眼病，其特征为角膜组织扩张、变薄以及向前的圆锥状突出，多见于青少年。早期检测和干预可防止角膜进一步扩张。现有的检查方法和技术诊断临床圆锥角膜并不困难，但在早期圆锥角膜（静止期圆锥角膜和亚临床圆锥角膜）的诊断方面存在局限性。在本研究中，我们通过对健康眼和营养不良性圆锥角膜进行Pentacam和Corvis ST检查，探讨了这两种仪器联合使用在临床圆锥角膜和亚临床圆锥角膜诊断中的价值。本研究为早期圆锥角膜的筛查和诊断提供了理论依据。分析显示，在所有纳入参数中，只有TP、SPA1、ARTh和bIOP呈正态分布，且只有bIOP具有等方差正态分布。TBI和CBI指数对亚临床圆锥角膜的诊断具有一定的敏感性和特异性，诊断能力较强，可用于圆锥角膜的筛查和早期诊断。
