Gottstein B, Witassek F, Eckert J
Schweiz Med Wochenschr. 1986 Jun 14;116(24):810-7.
The following new aspects of cystic and alveolar echinococcosis (= infections with the metacestode stages of Echinococcus granulosus and E. multilocularis respectively) are reported: identification of a Swiss E. granulosus isolate as "cattle strain" which differs from the "sheep strain"; new observations on proliferation and metastasis formation of larval E. multilocularis; information on chemotherapy of human echinococcosis; recent developments in immunoserology. The latter includes a new technique for serological differential diagnosis of cystic and alveolar echinococcosis, the determination of parasite-specific immunoglobulin classes (IgG, IgM, IgA and IgE) and circulating antigens in ELISA, and the introduction of arc-5 detection in routine serodiagnosis. A highly purified, species-specific antigen from E. multilocularis is now available for seroepidemiological studies.
本文报道了囊性和泡状棘球蚴病(分别为感染细粒棘球绦虫和多房棘球绦虫的中绦期幼虫)的以下新情况:鉴定出一株瑞士细粒棘球绦虫分离株为“牛株”,它与“羊株”不同;关于多房棘球绦虫幼虫增殖和转移形成的新观察结果;人体棘球蚴病化疗的相关信息;免疫血清学的最新进展。后者包括一种用于囊性和泡状棘球蚴病血清学鉴别诊断的新技术、在酶联免疫吸附测定(ELISA)中测定寄生虫特异性免疫球蛋白类别(IgG、IgM、IgA和IgE)及循环抗原,以及在常规血清诊断中引入arc - 5检测。现在有一种来自多房棘球绦虫的高度纯化的种特异性抗原可用于血清流行病学研究。