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[棘球蚴病的新发现]

[New findings on echinococcosis].

作者信息

Gottstein B, Witassek F, Eckert J

出版信息

Schweiz Med Wochenschr. 1986 Jun 14;116(24):810-7.

PMID:3523748
Abstract

The following new aspects of cystic and alveolar echinococcosis (= infections with the metacestode stages of Echinococcus granulosus and E. multilocularis respectively) are reported: identification of a Swiss E. granulosus isolate as "cattle strain" which differs from the "sheep strain"; new observations on proliferation and metastasis formation of larval E. multilocularis; information on chemotherapy of human echinococcosis; recent developments in immunoserology. The latter includes a new technique for serological differential diagnosis of cystic and alveolar echinococcosis, the determination of parasite-specific immunoglobulin classes (IgG, IgM, IgA and IgE) and circulating antigens in ELISA, and the introduction of arc-5 detection in routine serodiagnosis. A highly purified, species-specific antigen from E. multilocularis is now available for seroepidemiological studies.

摘要

本文报道了囊性和泡状棘球蚴病(分别为感染细粒棘球绦虫和多房棘球绦虫的中绦期幼虫)的以下新情况:鉴定出一株瑞士细粒棘球绦虫分离株为“牛株”,它与“羊株”不同;关于多房棘球绦虫幼虫增殖和转移形成的新观察结果;人体棘球蚴病化疗的相关信息;免疫血清学的最新进展。后者包括一种用于囊性和泡状棘球蚴病血清学鉴别诊断的新技术、在酶联免疫吸附测定(ELISA)中测定寄生虫特异性免疫球蛋白类别(IgG、IgM、IgA和IgE)及循环抗原,以及在常规血清诊断中引入arc - 5检测。现在有一种来自多房棘球绦虫的高度纯化的种特异性抗原可用于血清流行病学研究。

相似文献

1
[New findings on echinococcosis].[棘球蚴病的新发现]
Schweiz Med Wochenschr. 1986 Jun 14;116(24):810-7.
2
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Critical points in the immunodiagnosis of cystic echinococcosis in humans.人类囊性棘球蚴病免疫诊断中的关键点。
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Serological diagnosis of canine alveolar echinococcosis.犬肺泡型棘球蚴病的血清学诊断
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An international study on the serological differential diagnosis of human cystic and alveolar echinococcosis.一项关于人类囊性和肺泡性棘球蚴病血清学鉴别诊断的国际研究。
Bull World Health Organ. 1986;64(1):101-5.
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Serological differentiation between Echinococcus granulosus and E. multilocularis infections in man.人体中细粒棘球绦虫和多房棘球绦虫感染的血清学鉴别
Z Parasitenkd. 1983;69(3):347-56. doi: 10.1007/BF00927876.
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Serological diagnosis of echinococcosis: the diagnostic potential of native antigens.包虫病的血清学诊断:天然抗原的诊断潜力。
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[Study on the level of specific IgG, IgG1 and IgE during anaphylactic shock in sheep induced by Echinococcus granulosus].[细粒棘球绦虫诱导绵羊过敏性休克期间特异性IgG、IgG1和IgE水平的研究]
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2003;21(1):42-5.
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Cystic echinococcosis: progress and limits in epidemiology and immunodiagnosis.囊性棘球蚴病:流行病学与免疫诊断的进展及局限
Parassitologia. 2006 Jun;48(1-2):65-6.
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Improved serodiagnosis of alveolar echinococcosis of humans using an in vitro-produced Echinococcus multilocularis antigen.使用体外产生的多房棘球绦虫抗原改进人体肺泡型棘球蚴病的血清学诊断
Parasitology. 2007 Jun;134(Pt 6):879-88. doi: 10.1017/S0031182006002083. Epub 2007 Feb 19.

引用本文的文献

1
Echinococcus granulosus antigen 5 is closely related to proteases of the trypsin family.细粒棘球绦虫抗原5与胰蛋白酶家族的蛋白酶密切相关。
Biochem J. 2003 Jan 1;369(Pt 1):191-8. doi: 10.1042/BJ20021402.
2
Echinococcus granulosus antigens: immunoelectrophoretic and Western blot analysis of hydatid cyst fluids.细粒棘球绦虫抗原:包虫囊肿液的免疫电泳和蛋白质印迹分析
Parasitol Res. 1987;73(2):186-9. doi: 10.1007/BF00536480.
3
[The long-term course of 60 patients with alveolar echinococcosis in continuous therapy with mebendazole (1976-85)].
Klin Wochenschr. 1988 Nov 1;66(21):1060-73. doi: 10.1007/BF01711918.
4
Molecular and immunological diagnosis of echinococcosis.棘球蚴病的分子与免疫诊断
Clin Microbiol Rev. 1992 Jul;5(3):248-61. doi: 10.1128/CMR.5.3.248.