Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Student Research Committee, Department of Food Science and Technology, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Science and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Crit Rev Food Sci Nutr. 2023;63(25):7357-7377. doi: 10.1080/10408398.2022.2045894. Epub 2022 Mar 3.
, a frequent colonizer in the gut mucous layer of individuals, has constantly been recognized as a promising candidate for the next generation of probiotics due to its biological advantages from in vitro and in vivo investigations. This manuscript comprehensively reviewed the features of in terms of its function in host physiology and frequently utilized nutrition using the published peer-reviewed articles, which should present valuable and critical information to scientists, engineers, and even the general population. is an important bacterium that shows host physiology. However, its physiological advantages in several clinical settings also have excellent potential to become a probiotic. Consequently, it can be stated that there is a coherent and direct relation between the biological activities of the gut microbiota, intestinal dysbiosis/eubiosis, and the population of in the gut milieu, which is influenced by various genetical and nutritional factors. Current regulatory barriers, the need for large-scale clinical trials, and the feasibility of production must be removed before can be extensively used as a next-generation probiotic.
，一种经常定植于个体肠道黏膜层的菌属，由于其在体外和体内研究中表现出的生物学优势，一直被认为是下一代益生菌的有前途的候选者。本文综述了 在宿主生理学方面的功能及其常用营养物质的特征，使用了已发表的同行评议文章，这应该为科学家、工程师，甚至普通大众提供有价值和关键的信息。 是一种重要的细菌，表现出宿主生理学的特征。然而，其在几种临床环境中的生理优势也具有成为益生菌的巨大潜力。因此，可以说肠道微生物群的生物学活性、肠道失调/生态平衡以及肠道环境中 的种群之间存在着一致和直接的关系，而这受到各种遗传和营养因素的影响。在 可以广泛用作下一代益生菌之前，必须消除当前的监管障碍、大规模临床试验的需求和生产的可行性。
