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SUR1 As a New Therapeutic Target for Pulmonary Arterial Hypertension.SUR1作为肺动脉高压的新治疗靶点。
Am J Respir Cell Mol Biol. 2022 May;66(5):539-554. doi: 10.1165/rcmb.2021-0180OC.
2
Characterization of rare ABCC8 variants identified in Spanish pulmonary arterial hypertension patients.鉴定西班牙肺动脉高压患者中罕见 ABCC8 变异体的特征。
Sci Rep. 2020 Sep 15;10(1):15135. doi: 10.1038/s41598-020-72089-1.
3
Diazoxide-induced pulmonary hypertension in hyperinsulinaemic hypoglycaemia: Recommendations from a multicentre study in the United Kingdom.二氮嗪诱发高胰岛素血症性低血糖中的肺动脉高压：英国一项多中心研究的建议
Clin Endocrinol (Oxf). 2019 Dec;91(6):770-775. doi: 10.1111/cen.14096. Epub 2019 Oct 1.
4
Pulmonary Hypertension and ATP-Sensitive Potassium Channels.肺动脉高压与ATP敏感性钾通道
Hypertension. 2019 Jul;74(1):14-22. doi: 10.1161/HYPERTENSIONAHA.119.12992. Epub 2019 May 28.
5
Targeting TMEM16A to reverse vasoconstriction and remodelling in idiopathic pulmonary arterial hypertension.靶向 TMEM16A 逆转特发性肺动脉高压中的血管收缩和重构。
Eur Respir J. 2019 Jun 5;53(6). doi: 10.1183/13993003.00965-2018. Print 2019 Jun.
6
Loss-of-Function ABCC8 Mutations in Pulmonary Arterial Hypertension.肺动脉高压中的 ABCC8 功能丧失性突变。
Circ Genom Precis Med. 2018 Oct;11(10):e002087. doi: 10.1161/CIRCGEN.118.002087.
7
Ion Channels in Pulmonary Hypertension: A Therapeutic Interest?肺动脉高压中的离子通道：治疗学意义？
Int J Mol Sci. 2018 Oct 14;19(10):3162. doi: 10.3390/ijms19103162.
8
ATP-Sensitive Potassium Channels and Their Physiological and Pathophysiological Roles.三磷酸腺苷敏感性钾通道及其生理和病理生理作用。
Compr Physiol. 2018 Sep 14;8(4):1463-1511. doi: 10.1002/cphy.c170048.
9
Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis.肺动脉高压中血管外膜成纤维细胞的代谢和增殖状态通过微小RNA-124/PTBP1（多嘧啶序列结合蛋白1）/丙酮酸激酶肌肉轴进行调节。
Circulation. 2017 Dec 19;136(25):2468-2485. doi: 10.1161/CIRCULATIONAHA.117.028069. Epub 2017 Sep 26.
10
Identification of MicroRNA-124 as a Major Regulator of Enhanced Endothelial Cell Glycolysis in Pulmonary Arterial Hypertension via PTBP1 (Polypyrimidine Tract Binding Protein) and Pyruvate Kinase M2.通过PTBP1（多嘧啶序列结合蛋白）和丙酮酸激酶M2鉴定MicroRNA-124作为肺动脉高压中内皮细胞糖酵解增强的主要调节因子。
Circulation. 2017 Dec 19;136(25):2451-2467. doi: 10.1161/CIRCULATIONAHA.117.028034. Epub 2017 Sep 26.

Targeting ATP-Sensitive K Channels to Treat Pulmonary Hypertension.

作者信息

Breen Ellen, Yuan Jason X-J

机构信息

Department of Medicine University of California San Diego La Jolla, CA.

出版信息

Am J Respir Cell Mol Biol. 2022 May;66(5):476-478. doi: 10.1165/rcmb.2021-0549ED.

DOI:10.1165/rcmb.2021-0549ED
PMID:35238728
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9116352/
Abstract
摘要