Vangelov S, Iovchev E, Simov I, Mentov V
Vet Med Nauki. 1986;23(1):3-9.
Studied were the therapeutic and prophylactic effects of the preparation Gentavet (containing gentamycin complex II) with pigs, birds and calves affected with colibacteriosis. It was found that in conc. 80,000 IU (0.08 g or 0.8 g) with the drinking water (1 lit.) given 14 days to birds lowered the mortality rate to a higher extent than Avimycin (containing oxitetracycline and neomycin). At the rate of 10,000 IU (0.01 g or 0.1 g) per kg body mass, orally, split in two for 24 h with newborn pigs Gentavet produced a very good prophylactic effect, and when used at a higher rate--16,000 IU (0.016 g or 0.16 g) per kg under the same conditions up to 90 per cent of the pigs with polyenteritis recovered. At 10,000 IU (0.01 g or 0.1 g) per kg body mass, orally, split in two for 24 h with newborn calves with colibacteriosis produced therapeutic and prophylactic effects. Gentamycin complex II residual amounts remained longest in the parenchymal tissue of the kidneys and liver. The withdrawal times in slaughtering birds, pigs, and calves treated with Gentavet should last from 30 to 46 days (31 days for birds, 46 days for pigs and calves of up to 100 kg, and 30 days for heifers of up to 400-500 kg). This period could be shortened 4 to 5 days if both kidneys and liver are to be eliminated after slaughter.
研究了复方庆大霉素（含庆大霉素复合物 II）对患大肠杆菌病的猪、禽和犊牛的治疗及预防效果。结果发现，在饮水中添加 80,000 IU（0.08 g 或 0.8 g）并给禽类连续饮用 14 天，其降低死亡率的效果比阿维菌素（含土霉素和新霉素）更好。对于新生仔猪，按每千克体重 10,000 IU（0.01 g 或 0.1 g）口服，分两次在 24 小时内喂服，复方庆大霉素产生了很好的预防效果；在相同条件下，以更高剂量——每千克体重 16,000 IU（0.016 g 或 0.16 g）使用时，高达 90%的患多发性肠炎的猪康复。对于患大肠杆菌病的新生犊牛，按每千克体重 10,000 IU（0.01 g 或 0.1 g）口服，分两次在 24 小时内喂服，产生了治疗和预防效果。庆大霉素复合物 II 在肾脏和肝脏实质组织中的残留量持续时间最长。用复方庆大霉素治疗的禽类、猪和犊牛的屠宰休药期应为 30 至 46 天（禽类为 31 天，体重达 100 kg 的猪和犊牛为 46 天，体重达 400 - 500 kg 的小母牛为 30 天）。如果屠宰后去除肾脏和肝脏，则该期限可缩短 4 至 5 天。
