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55 岁以下患者全髋关节置换术的中期生存情况。

Mid-Term Survival of Total Hip Arthroplasty in Patients Younger Than 55-year-old.

机构信息

Joint Implant Surgeons, Inc, New Albany, OH; White Fence Surgical Suites, New Albany, OH; Mount Carmel Health System, New Albany, OH; Department of Orthopaedics, The Ohio State University College of Medicine, Columbus, OH.

Joint Implant Surgeons, Inc, New Albany, OH; White Fence Surgical Suites, New Albany, OH; Mount Carmel Health System, New Albany, OH.

出版信息

J Arthroplasty. 2022 Jul;37(7S):S517-S523. doi: 10.1016/j.arth.2022.02.092. Epub 2022 Feb 28.

Abstract

BACKGROUND

Survivorship of total hip arthroplasty (THA) in younger patients is concerning given the inverse relationship between age and lifetime risk for revision. The purpose of this study is to determine if risk of revision has improved for patients aged 55 years or younger who undergo primary THA using modern polyethylene liners.

METHODS

A retrospective review identified 2,461 consented patients (2,814 hips) with minimum 2-year follow-up who underwent primary THA at our institution between September 2007 and August 2014 using components from a single manufacturer (Zimmer Biomet), all with vitamin E-infused highly crosslinked polyethylene acetabular inserts. There were 561 patients (643 THA; 23%) aged 55 or younger and 1,900 (2,171 THA; 77%) older than 55.

RESULTS

Mean follow-up was 5.0 years for both groups. There were more male patients in the younger (55%) than older (41%) group. Body mass index (BMI) was higher in younger patients independent of gender. Improvement in Harris hip score (HHS) was similar between groups. Kaplan-Meier survival to endpoint of all cause revision was similar between groups at 12 years (P = .8808) with 97.5% (95% CI: ±0.7%) for younger versus 97.1% (95% CI: ±0.6%) for older patients. Most frequent reason for revision overall was periprosthetic femoral fracture (21; 0.75%); univariate analysis revealed risk factors were female gender (P = .28) and age ≥65 years (P = .012).

CONCLUSION

Use of modern polyethylene, such as vitamin E-stabilized highly cross-linked, liners during THA may improve survivorship in younger patients undergoing THA. Younger patients undergoing primary THA with highly cross-linked polyethylene liners had no increased rate of revision at mid-term follow-up.

摘要

背景

对于接受全髋关节置换术(THA)的年轻患者,考虑到年龄与翻修终生风险之间的反比关系,其生存率令人担忧。本研究旨在确定使用现代聚乙烯衬垫进行初次 THA 的 55 岁或以下患者的翻修风险是否有所改善。

方法

回顾性分析了 2007 年 9 月至 2014 年 8 月期间在我院接受初次 THA 的 2461 名(2814 髋)接受过知情同意的患者,这些患者均来自单一制造商(捷迈邦美),均使用维生素 E 稳定的高交联聚乙烯髋臼衬垫。55 岁或以下患者 561 例(643 髋,23%),55 岁以上患者 1900 例(2171 髋,77%)。

结果

两组患者的平均随访时间均为 5.0 年。年轻组(55%)的男性患者多于老年组(41%)。无论性别如何,年轻患者的体重指数(BMI)均较高。两组的 Harris 髋关节评分(HHS)改善情况相似。两组在 12 年时的全因翻修终点的 Kaplan-Meier 生存率相似(P=0.8808),年轻组为 97.5%(95%CI:±0.7%),老年组为 97.1%(95%CI:±0.6%)。总体而言,最常见的翻修原因是假体周围股骨骨折(21 例;0.75%);单因素分析显示,危险因素为女性(P=0.28)和年龄≥65 岁(P=0.012)。

结论

在初次 THA 中使用现代聚乙烯(如维生素 E 稳定的高交联聚乙烯)衬垫可能会提高年轻患者的生存率。在中期随访中,使用高交联聚乙烯衬垫接受初次 THA 的年轻患者的翻修率没有增加。

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