Jones J D, Varghese D, Pabary R, Langley R J
Infection Medicine, University of Edinburgh, United Kingdom.
Department of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Children, Glasgow, United Kingdom.
Paediatr Respir Rev. 2022 Dec;44:70-77. doi: 10.1016/j.prrv.2022.02.001. Epub 2022 Feb 12.
The looming antibiotic resistance crisis is forcing clinicians to consider alternative approaches to treating bacterial infections. As the window of use for current antimicrobial agents becomes ever narrower, we consider if looking back will now be the way forward. Conceptually, phage therapy is simple and specific; a targeted treatment to control bacterial overgrowth. In this article we discuss bacteriophage and potential use in future therapy.
迫在眉睫的抗生素耐药性危机正迫使临床医生考虑治疗细菌感染的替代方法。随着当前抗菌药物的使用窗口变得越来越窄，我们思考回顾过去是否会成为前进的方向。从概念上讲，噬菌体疗法简单且具有特异性；是一种控制细菌过度生长的靶向治疗方法。在本文中，我们将讨论噬菌体及其在未来治疗中的潜在用途。
