Department of Pediatrics, Qilu Hospital, Shandong University, No.107, West of Wenhua Road, 250012, Jinan, People's Republic of China.
School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, 250012, People's Republic of China.
Sci Rep. 2022 Mar 3;12(1):3510. doi: 10.1038/s41598-022-07584-8.
To compare the efficacy of peripherally inserted central catheters (PICCs) and totally implantable venous-access ports (TIVAPs) for chemotherapy of pediatric patients with malignant tumors. A total of 96 children with malignant tumors who received catheterization of PICCs or TIVAPs for chemotherapy from May 2020 to May 2021 in Department of Pediatric Oncology of Qilu Hospital of Shandong University were selected. Then, the pathological features of disease, the age of children, the indwelling time, the incidence of postoperative complications, and the satisfaction degree were compared between the two groups. The age of children in the TIVAP group was younger than that in the PICC group (P < 0.05). The indwelling time in the TIVAP group was 7.2 ± 2.757 months,which was significantly longer than 5.65 ± 2.058 months in the PICC group (P < 0.05). The incidence of postoperative complications in the TIVAP group without systemic or local infection was markedly lower than that in the PICC group (P < 0.05). The satisfaction degree of patients in the TIVAP group without unsatisfied was markedly higher than that in the PICC group (P < 0.05). TIVAPs may be the first choice for chemotherapy of children with malignant tumors.
比较经外周静脉穿刺中心静脉置管（PICC）和完全植入式静脉输液港（TIVAP）在儿科恶性肿瘤患者化疗中的疗效。选取 2020 年 5 月至 2021 年 5 月在山东大学齐鲁医院小儿肿瘤科行 PICC 或 TIVAP 置管化疗的 96 例恶性肿瘤患儿，比较两组患儿疾病病理特征、年龄、置管时间、术后并发症发生率及满意度。TIVAP 组患儿年龄小于 PICC 组（P＜0.05）。TIVAP 组置管时间 7.2±2.757 个月，明显长于 PICC 组的 5.65±2.058 个月（P＜0.05）。TIVAP 组无全身或局部感染的术后并发症发生率明显低于 PICC 组（P＜0.05）。TIVAP 组无不满意的患者满意度明显高于 PICC 组（P＜0.05）。TIVAP 可作为儿科恶性肿瘤化疗的首选。
