Alshurafa Awni, Sied Mustafa, Elkhdier Maab, Abdalhadi Ahmed M, Yassin Mohamed A
Hamad Medical Corporation, Doha, Qatar.
IDCases. 2022 Feb 12;27:e01451. doi: 10.1016/j.idcr.2022.e01451. eCollection 2022.
Hypereosinophilic syndromes (HES) are a group of uncommon disorders characterized by persistent eosinophils overproduction which can lead to tissue damage and organs dysfunction secondary to eosinophils tissue infiltration and inflammatory mediators' release. Causes of secondary HES include parasitic infection, some solid tumors, underlying connective tissue disease, allergic conditions and T cell lymphoma. has been reported only once as a cause of secondary HES in the literature. We report the second case of infection in 29-year-old male patient who presents with HES and secondary Immune thrombocytopenic purpura (ITP). This case is different from the first reported case by the presence of HES complication on presentation manifesting as portal vein thrombosis, which was further complicated by ischemic colitis. eradication therapy alone was successful in a resolution of hypereosinophilia and platelets recovery without the need of corticosteroids or any other treatment.
高嗜酸性粒细胞综合征（HES）是一组罕见的疾病，其特征是嗜酸性粒细胞持续过度产生，这可导致组织损伤和器官功能障碍，继发于嗜酸性粒细胞组织浸润和炎症介质释放。继发性HES的病因包括寄生虫感染、一些实体瘤、潜在的结缔组织病、过敏情况和T细胞淋巴瘤。在文献中，[具体病因]仅作为继发性HES的病因被报道过一次。我们报告了第二例29岁男性患者感染[具体病因]的病例，该患者患有HES和继发性免疫性血小板减少性紫癜（ITP）。该病例与首例报告病例的不同之处在于，患者就诊时存在HES并发症，表现为门静脉血栓形成，并进一步并发缺血性结肠炎。单独的[具体病因]根除治疗成功地解决了嗜酸性粒细胞增多症并使血小板恢复，无需使用皮质类固醇或任何其他治疗。
