Geary T G, Boland M T, Jensen J B
Am J Trop Med Hyg. 1986 Jul;35(4):704-7. doi: 10.4269/ajtmh.1986.35.704.
Cultured Plasmodium falciparum was retarded in intraerythrocytic development by serum from malaria-immune adults, by human TB serum, and by rabbit tumor necrosis serum. Neither the potency nor efficacy of any of these sera was altered by a variety of antioxidants or oxygen-free radial scavengers, including ascorbate, alpha-tocopherol, BHT, cystine or cysteine, glutathione, histidine, phenylalanine, tryptophan, tyrosine, superoxide dismutase, catalase (or combination of the two enzymes), or by reducing the ambient O2 tension to 1%. It is thus unlikely that the antiparasitic activity of these inhibitory sera can be attributed to oxidative mechanisms.
来自疟疾免疫成人的血清、人结核血清和兔肿瘤坏死血清可抑制体外培养的恶性疟原虫在红细胞内的发育。多种抗氧化剂或氧自由基清除剂，包括抗坏血酸、α-生育酚、丁基羟基甲苯、胱氨酸或半胱氨酸、谷胱甘肽、组氨酸、苯丙氨酸、色氨酸、酪氨酸、超氧化物歧化酶、过氧化氢酶（或这两种酶的组合），或者将环境氧气张力降低到1%，均不会改变这些血清的效力或功效。因此，这些抑制性血清的抗寄生虫活性不太可能归因于氧化机制。
