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Structural dynamics determine voltage and pH gating in human voltage-gated proton channel.

机构信息

Department of Cell Biology and Biophysics, School of Biological and Chemical Sciences, University of Missouri-Kansas City, Kansas City, United States.

出版信息

Elife. 2022 Mar 4;11:e73093. doi: 10.7554/eLife.73093.

DOI:10.7554/eLife.73093
PMID:35244539
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8926398/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/ae7435e57d16/elife-73093-sa2-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/fc34445eae4d/elife-73093-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/1138fff4ed16/elife-73093-fig1-figsupp1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/04263e9033ce/elife-73093-fig1-figsupp2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/2d2e5c389932/elife-73093-fig1-figsupp3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/cea901ab4056/elife-73093-fig1-figsupp4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/c05f11571cdb/elife-73093-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/148e9db604d4/elife-73093-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/0e35e64496b6/elife-73093-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/751e73f0de60/elife-73093-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/c58f827ea57a/elife-73093-sa2-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/181ecb3ff013/elife-73093-sa2-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/ae7435e57d16/elife-73093-sa2-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/fc34445eae4d/elife-73093-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/1138fff4ed16/elife-73093-fig1-figsupp1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/04263e9033ce/elife-73093-fig1-figsupp2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/2d2e5c389932/elife-73093-fig1-figsupp3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/cea901ab4056/elife-73093-fig1-figsupp4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/c05f11571cdb/elife-73093-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/148e9db604d4/elife-73093-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/0e35e64496b6/elife-73093-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/751e73f0de60/elife-73093-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/c58f827ea57a/elife-73093-sa2-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/181ecb3ff013/elife-73093-sa2-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0108/8926398/ae7435e57d16/elife-73093-sa2-fig3.jpg

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Voltage-dependent structural models of the human Hv1 proton channel from long-timescale molecular dynamics simulations.
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