Edelman A S, Sanchez P L, Robinson M E, Hochwald G M, Thorbecke G J
Avian Dis. 1986 Jan-Mar;30(1):105-11.
Wattle responses of 2-to-8-week-old chickens to phytohemagglutinins PHA-P and PHA-M were studied. Dilutions of PHA-M that did not induce wattle swelling after one injection did cause readily detectable swelling when injected a second time 1 week later. These responses were absent in birds subjected to thymectomy and gamma-irradiation at hatching and in birds treated with cyclosporin A during the week of sensitization, indicating that these responses are T-cell-dependent. Chickens bearing transplantable fibrosarcomas failed to show responses. It is suggested that reactivity to a second injection of PHA-M may be used as a measure of immunocompetence at the T-cell level in very young chickens.
研究了2至8周龄鸡对植物血凝素PHA - P和PHA - M的肉垂反应。一次注射后未引起肉垂肿胀的PHA - M稀释液，在1周后第二次注射时确实会引起易于检测到的肿胀。在孵化时接受胸腺切除术和γ射线照射的鸡以及在致敏周期间用环孢菌素A处理的鸡中没有这些反应，这表明这些反应是T细胞依赖性的。携带可移植纤维肉瘤的鸡未能表现出反应。有人提出，对第二次注射PHA - M的反应性可作为衡量幼龄鸡T细胞水平免疫能力的一种方法。
