在一个大型的、本地的、入选的初级保健人群中，使用事件发生时间分析比较接种疫苗与自然感染后2019冠状病毒病突破性住院的真实世界发病率。

Real-World Incidence of Breakthrough Coronavirus Disease 2019 Hospitalization After Vaccination vs Natural Infection in a Large, Local, Empaneled Primary Care Population Using Time-to-Event Analysis.

作者信息

Pollock Benjamin D, Storlie Curtis B, Tande Aaron J, Sampathkumar Priya

机构信息

Division of Health Care Delivery Research, Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Jacksonville, Florida, USA.

Division of Data Science, Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, USA.

出版信息

Clin Infect Dis. 2022 Sep 30;75(7):1239-1241. doi: 10.1093/cid/ciac186.

DOI:10.1093/cid/ciac186

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8903437/

Abstract

We followed 106 349 primary care patients for 22 385 3099 person-days across 21 calendar months and documented 69 breakthrough coronavirus disease 2019 (COVID-19) hospitalizations: 65/102,613 (0.06%) among those fully vaccinated, 3/11 047 (0.03%) among those previously infected, and 1/7,313 (0.01%) among those with both statuses. These data give providers real-world context regarding breakthrough COVID-19 hospitalization risk.

摘要

我们在21个日历月内对106349名初级保健患者进行了为期223853099人日的随访，并记录了69例突破性新型冠状病毒肺炎（COVID-19）住院病例：在完全接种疫苗的患者中，有65/102613（0.06%）；在既往感染过的患者中，有3/11047（0.03%）；在兼具两种情况的患者中，有1/7313（0.01%）。这些数据为医疗服务提供者提供了关于突破性COVID-19住院风险的真实情况。

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