聚维酮碘对伤口愈合影响的研究。
A study of the effect of povidone-iodine on wound healing.
作者信息
Gilmore O J, Reid C, Strokon A
出版信息
Postgrad Med J. 1977 Mar;53(617):122-5. doi: 10.1136/pgmj.53.617.122.
Abstract
The effect of dry powder povidone-iodine (Disadine D.P.) on wound healing was assessed experimentally and clinically. It did not interfere with wound healing macroscopically, histologically or mechanically in Wistar rats. One hundred and one patients undergoing 'clean' elective surgery were included in the controlled clinical study and povidone-iodine did not affect wound healing in any way. In the control group 4% of patients developed infection compared with none of those sprayed with povidone-iodine. No adverse reaction to povidone-iodine was seen in either study. This antiseptic offers a safe alternative to antibiotics for use at operation whenever there is risk of wound infection from operative bacterial contamination.
摘要
对碘伏干粉（迪赛定D.P.）对伤口愈合的影响进行了实验和临床评估。在Wistar大鼠中，它在宏观、组织学或力学方面均未干扰伤口愈合。101例接受“清洁”择期手术的患者纳入了对照临床研究，碘伏对伤口愈合没有任何影响。对照组有4%的患者发生感染，而喷洒碘伏的患者无一感染。两项研究均未观察到对碘伏的不良反应。对于任何因手术细菌污染而有伤口感染风险的手术，这种防腐剂为抗生素提供了一种安全的替代品。
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本文引用的文献
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