Jasty M J, Floyd W E, Schiller A L, Goldring S R, Harris W H
J Bone Joint Surg Am. 1986 Jul;68(6):912-9.
We are reporting four cases of extensive, localized bone resorption adjacent to a rigidly anchored, cemented total hip replacement. None of these hips showed evidence of infection on clinical, bacteriological, or pathological evaluation. The tissue from the regions of osteolysis showed sheets of macrophages and foreign-body giant cells invading the femoral cortices. Abundant methylmethacrylate particulate debris was present in the tissues, but polyethylene wear debris was absent. The histological appearance of this tissue resembled that reported about loosened total hip implants with the exception of the synovial-like layer at the cement surface. The cases reported here show that aggressive bone lysis may occur around stable cemented total hip arthroplasties without the presence of sepsis or malignant disease.
我们报告了4例紧邻牢固固定的骨水泥型全髋关节置换物出现广泛局部骨吸收的病例。经临床、细菌学及病理学评估，这些髋关节均未显示感染迹象。骨溶解区域的组织显示有大量巨噬细胞和异物巨细胞侵入股皮质。组织中存在大量甲基丙烯酸甲酯颗粒碎片，但无聚乙烯磨损碎片。除了骨水泥表面的滑膜样层外，该组织的组织学表现与报道的松动全髋关节植入物相似。本文报道的病例表明，在稳定的骨水泥型全髋关节置换周围可能发生侵袭性骨溶解，而不存在败血症或恶性疾病。
