Araj G F, Majeed H A
J Hyg (Lond). 1986 Aug;97(1):133-8. doi: 10.1017/s0022172400064421.
A two-minute strep A direct swab test (SADST) was used to detect the presence of Lancefield group A streptococci (GAS) from the throats of 207 patients with pharyngitis at a primary-care clinic. The results were compared with a standard culture method. Fifty-one specimens were positive and 156 specimens were negative for GAS by culture. The SADST had a sensitivity of 96% (49 of 51) and specificity of 98.7% (154 of 156). The predictive values of a positive and negative SADST, for GAS, were 96% and 98.7% respectively. The SADST showed negative reactions with five specimens containing beta-haemolytic streptococci other than GAS and 34 known stock cultures other than GAS. Our results indicate that SADST is a rapid, simple, convenient and reliable test to use for diagnosis of GAS pharyngitis at primary care clinics, physicians' offices and clinical laboratories.
采用两分钟A群链球菌直接拭子检测法(SADST),对一家初级保健诊所的207例咽炎患者咽喉部进行A群兰氏链球菌(GAS)检测。将结果与标准培养方法进行比较。通过培养,51份标本GAS呈阳性,156份标本GAS呈阴性。SADST的敏感性为96%(51份中的49份),特异性为98.7%(156份中的154份)。SADST对GAS阳性和阴性的预测值分别为96%和98.7%。SADST对5份含非GAS的β溶血性链球菌标本以及34份非GAS的已知标准菌株培养物均呈阴性反应。我们的结果表明,SADST是一种快速、简单、便捷且可靠的检测方法,可用于初级保健诊所、医生办公室和临床实验室诊断GAS咽炎。