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维生素D的独特代谢

The extraordinary metabolism of vitamin D.

作者信息

Wagner Carol L, Hollis Bruce W

机构信息

Division of Neonatology, Shawn Jenkins Children's Hospital, Charleston, United States.

Darby Children's Research Institute, Medical University of South Carolina, Charleston, United States.

出版信息

Elife. 2022 Mar 8;11:e77539. doi: 10.7554/eLife.77539.

DOI:10.7554/eLife.77539
PMID:35257657
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8903826/
Abstract

The placenta plays an important role in how vitamin D is metabolized and supplied to the fetus.

摘要

胎盘在维生素D的代谢及向胎儿的供应过程中起着重要作用。

相似文献

1
The extraordinary metabolism of vitamin D.维生素D的独特代谢
Elife. 2022 Mar 8;11:e77539. doi: 10.7554/eLife.77539.
2
Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit.胎盘对 25(OH)维生素 D 的摄取和代谢决定了其在胎-胎盘单位中的活性。
Elife. 2022 Mar 8;11:e71094. doi: 10.7554/eLife.71094.
3
Vitamin D and pregnancy: the maternal-fetal metabolism of vitamin D.维生素D与妊娠：维生素D的母胎代谢
Endocr Rev. 1981 Summer;2(3):264-74. doi: 10.1210/edrv-2-3-264.
4
Perinatal metabolism of vitamin D: transition from fetal to neonatal life.
Clin Perinatol. 1981 Jun;8(2):287-306.
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Elevated fibroblast growth factor 23 exerts its effects on placenta and regulates vitamin D metabolism in pregnancy of Hyp mice.升高的成纤维细胞生长因子 23 对胎盘发挥作用，并调节 Hyp 小鼠妊娠期间的维生素 D 代谢。
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Vitamin C in the placenta and fetal organs in malaria.
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Vitamin D metabolism and function during pregnancy and the neonatal period.孕期及新生儿期的维生素D代谢与功能
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Maternal vitamin D sufficiency and reduced placental gene expression in angiogenic biomarkers related to comorbidities of pregnancy.母体维生素D充足与妊娠合并症相关血管生成生物标志物中胎盘基因表达降低。
J Steroid Biochem Mol Biol. 2017 Oct;173:273-279. doi: 10.1016/j.jsbmb.2017.02.003. Epub 2017 Feb 13.
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Vitamin D metabolism during pregnancy.
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Vitamin D in the maternal-fetal-neonatal interface: clinical implications and requirements for supplementation.母婴-新生儿界面中的维生素D：临床意义及补充需求
J Matern Fetal Neonatal Med. 2013 May;26(7):633-8. doi: 10.3109/14767058.2012.746306. Epub 2012 Dec 14.

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Children (Basel). 2025 May 26;12(6):682. doi: 10.3390/children12060682.
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Vitamin D-related risk factors for preterm and full-term infants at birth: a retrospective study.出生时早产和足月婴儿的维生素D相关风险因素：一项回顾性研究。
BMC Pediatr. 2025 May 24;25(1):417. doi: 10.1186/s12887-025-05765-8.
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Vitamin D Levels and Depressive Symptoms during Pregnancy: A Prospective Pregnancy Cohort Study.孕期维生素D水平与抑郁症状：一项前瞻性妊娠队列研究。
Depress Anxiety. 2024 Aug 8;2024:1788167. doi: 10.1155/2024/1788167. eCollection 2024.
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Vitamin D: What We Know and What We Still Do Not Know About Vitamin D in Preterm Infants-A Literature Review.维生素D：关于早产儿维生素D我们所知道的和仍然未知的——一篇文献综述
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Pregnancy, Breastfeeding, and Vitamin D.妊娠、哺乳与维生素 D
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Genomic or Non-Genomic? A Question about the Pleiotropic Roles of Vitamin D in Inflammatory-Based Diseases.基因组或非基因组？维生素 D 在炎症相关疾病中的多效作用之问。
Nutrients. 2023 Feb 2;15(3):767. doi: 10.3390/nu15030767.
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Immune-metabolic adaptations in pregnancy: A potential stepping-stone to sepsis.妊娠期间的免疫代谢适应性：脓毒症的潜在契机。
EBioMedicine. 2022 Dec;86:104337. doi: 10.1016/j.ebiom.2022.104337. Epub 2022 Dec 2.
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Relevance of Vitamin D and Its Deficiency for the Ovarian Follicle and the Oocyte: An Update.维生素 D 及其缺乏与卵泡和卵母细胞的相关性：最新研究进展。
Nutrients. 2022 Sep 9;14(18):3712. doi: 10.3390/nu14183712.

本文引用的文献

1
Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit.胎盘对 25(OH)维生素 D 的摄取和代谢决定了其在胎-胎盘单位中的活性。
Elife. 2022 Mar 8;11:e71094. doi: 10.7554/eLife.71094.
2
Effects of vitamin D supplementation on circulating concentrations of growth factors and immune-mediators in healthy women during pregnancy.孕期补充维生素 D 对健康女性循环中生长因子和免疫介质浓度的影响。
Pediatr Res. 2021 Feb;89(3):554-562. doi: 10.1038/s41390-020-0885-7. Epub 2020 Apr 20.
3
Effects of Maternal Vitamin D3 Supplementation on Offspring Epigenetic Clock of Gestational Age at Birth: A Post-hoc Analysis of a Randomized Controlled Trial.孕期补充维生素D3对出生时胎龄后代表观遗传时钟的影响：一项随机对照试验的事后分析
Epigenetics. 2020 Aug;15(8):830-840. doi: 10.1080/15592294.2020.1734148. Epub 2020 Mar 1.
4
Significant correlation between regulatory T cells and vitamin D status in term and preterm labor.足月和早产临产与调节性 T 细胞和维生素 D 状态有显著相关性。
J Reprod Immunol. 2018 Sep;129:15-22. doi: 10.1016/j.jri.2018.07.004. Epub 2018 Jul 18.
5
Biology and Mechanisms of Action of the Vitamin D Hormone.维生素 D 激素的生物学与作用机制。
Endocrinol Metab Clin North Am. 2017 Dec;46(4):815-843. doi: 10.1016/j.ecl.2017.07.001. Epub 2017 Sep 29.
6
Maternal vitamin D sufficiency and reduced placental gene expression in angiogenic biomarkers related to comorbidities of pregnancy.母体维生素D充足与妊娠合并症相关血管生成生物标志物中胎盘基因表达降低。
J Steroid Biochem Mol Biol. 2017 Oct;173:273-279. doi: 10.1016/j.jsbmb.2017.02.003. Epub 2017 Feb 13.
7
Early pregnancy vitamin D status and risk of preeclampsia.早期妊娠维生素D状态与子痫前期风险
J Clin Invest. 2016 Dec 1;126(12):4702-4715. doi: 10.1172/JCI89031. Epub 2016 Nov 14.
8
Clinical review: The role of the parent compound vitamin D with respect to metabolism and function: Why clinical dose intervals can affect clinical outcomes.临床综述：母体化合物维生素 D 在代谢和功能方面的作用：为何临床剂量间隔会影响临床结果。
J Clin Endocrinol Metab. 2013 Dec;98(12):4619-28. doi: 10.1210/jc.2013-2653. Epub 2013 Oct 8.
9
Vitamin D supplementation during pregnancy: double-blind, randomized clinical trial of safety and effectiveness.孕期补充维生素 D：安全性和有效性的双盲、随机临床试验。
J Bone Miner Res. 2011 Oct;26(10):2341-57. doi: 10.1002/jbmr.463.
10
Vitamin D and pregnancy: the maternal-fetal metabolism of vitamin D.维生素D与妊娠：维生素D的母胎代谢
Endocr Rev. 1981 Summer;2(3):264-74. doi: 10.1210/edrv-2-3-264.