Ahmed Jaafar Omer, Ahmad Shwan Abdubakr, Hassan Marwan Nasih, Kakamad Fahmi H, Salih Rawezh Q, Abdulla Berwn A, Rahim Fattah Fattah Hama, Mohammed Shvan H, Ali Razhan K, Salih Abdulwahid M
Kscien Organization, Hamdi Str, Azadi Mall, Sulaimani, Kurdistan, Iraq.
Mental Health Treatment Center, Madam Mitterrand Street, Sulaimani, Iraq.
Ann Med Surg (Lond). 2022 Apr;76:103440. doi: 10.1016/j.amsu.2022.103440. Epub 2022 Mar 3.
Despite numerous studies regarding neurological manifestations and complications of COVID-19, only a few cases of neurological consequences following complete recovery from SARS-CoV-2 infection have been described.
The current study aims to present a quantitative meta-analysis of published studies regarding the post-infectious neurological complications of COVID-19.
The Web of Science, PubMed, MEDLINE on OVID, and Google scholar were searched for English-language researches published after January 1, 2020.
The review of the literature revealed 60 cases - of which 40 (66.7%) cases were male, and 18 (30%) were female. The average age was 44.95 years. Overall, 17 (28.3%) patients had comorbid conditions. Twenty-four (40%) patients were hospitalized during an active COVID-19 infection. The average interval from the COVID-19 infection to the onset of neurological sequelae was 33.2 days. Guillain-Barre syndrome was the most commonly reported neurological condition (15, 25%).
Despite recovery from acute infection, the pandemic highlights the significance of ongoing, comprehensive follow-up of all COVID-19 patients - even those initially were believed to be asymptomatic.
尽管有大量关于新冠病毒病(COVID-19)神经学表现和并发症的研究,但仅有少数几例在从严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染完全康复后出现神经学后果的病例被描述。
本研究旨在对已发表的关于COVID-19感染后神经并发症的研究进行定量荟萃分析。
检索了科学网、PubMed、OVID上的MEDLINE以及谷歌学术,以查找2020年1月1日之后发表的英文研究。
文献综述发现了60例病例,其中40例(66.7%)为男性,18例(30%)为女性。平均年龄为44.95岁。总体而言,17例(28.3%)患者有合并症。24例(40%)患者在COVID-19感染活跃期住院。从COVID-19感染到神经后遗症发作的平均间隔时间为33.2天。吉兰-巴雷综合征是最常报告的神经疾病(15例,25%)。
尽管从急性感染中康复,但这场大流行凸显了对所有COVID-19患者进行持续、全面随访的重要性,即使是那些最初被认为无症状的患者。