Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
BMC Womens Health. 2022 Mar 9;22(1):66. doi: 10.1186/s12905-022-01646-9.
Standardized tools are used to measure health-related quality of life (HRQoL) and they focus on selected physical, emotional, and social functioning. This approach may miss out on the heterogeneity of HRQoL among various sub-populations. The patient-generated index (PGI) is a tool used to measure HRQoL based on patients' expectations. Among patients living with HIV, HRQoL is an important indicator as the world moves beyond the UNAIDS 90-90-90 goals, towards the so-called fourth 90 that aims at good HRQoL. We compared the PGI and the Euroqol 5 Dimension 3-level (EQ-5D-3L) to identify areas of importance to pregnant women living with HIV affecting thier HRQoL.
Through convenience sampling, we surveyed 100 pregnant women living with HIV attending antenatal and postnatal clinics in Western Kenya, using both the PGI and the EQ-5D-3L questionnaires. A PGI score and EQ-5D-3L index were generated for each participant. Data from the PGI was also summarized into themes. The PGI scores and EQ-5D-3L index scores were correlated using Pearson correlation.
From the PGI tool, 64% of the women reported having two to three main priority areas of their lives affected by their HIV status. These areas centered on themes of economic wellbeing (84% of the women), physical health (58%), psychological/emotional health (49%), and relationships (28%). The mean PGI score was 2.01 [SD = 1.10; median 1.10]. The majority of the women reported having no problems in any of the 5 dimensions captured in the EQ-5D-3L. The mean EQ-5D-3L score was 0.94 [SD = 1.10; median 1.00]. Both the EQ-5D-3L and the PGI showed less than perfect HRQoL. There was no correlation between the PGI and the EQ-5D-3L scores.
The PGI may capture aspects of contextual social and emotional life for Kenyan pregnant women living with HIV that are not identified by generic tools. Highlighting areas of importance to patients' HRQoL is key as focus shifts towards the fourth 90 and may also inform the design of care programs aligned to patient needs.
标准化工具用于测量与健康相关的生活质量（HRQoL），并侧重于特定的身体、情感和社会功能。这种方法可能会忽略不同亚人群中 HRQoL 的异质性。患者生成指数（PGI）是一种基于患者预期来测量 HRQoL 的工具。在感染艾滋病毒的患者中，HRQoL 是一个重要的指标，因为世界正在超越 UNAIDS 的 90-90-90 目标，迈向所谓的第四个 90，旨在实现良好的 HRQoL。我们比较了 PGI 和 EuroQol 5 维度 3 级（EQ-5D-3L），以确定影响感染艾滋病毒的孕妇 HRQoL 的重要领域。
通过便利抽样，我们在肯尼亚西部的产前和产后诊所调查了 100 名感染艾滋病毒的孕妇，使用 PGI 和 EQ-5D-3L 问卷。为每位参与者生成 PGI 评分和 EQ-5D-3L 指数。从 PGI 工具获得的数据也被总结为主题。使用 Pearson 相关系数对 PGI 评分和 EQ-5D-3L 指数评分进行相关性分析。
从 PGI 工具中，64%的女性报告说她们的生活中有两个到三个主要优先领域受到 HIV 状况的影响。这些领域集中在经济福利（84%的女性）、身体健康（58%）、心理/情绪健康（49%）和人际关系（28%）主题上。PGI 评分的平均值为 2.01 [SD=1.10；中位数 1.10]。大多数女性报告说，在 EQ-5D-3L 中捕获的五个维度中没有任何问题。EQ-5D-3L 的平均评分是 0.94 [SD=1.10；中位数 1.00]。PGI 和 EQ-5D-3L 都显示出低于完美的 HRQoL。PGI 评分和 EQ-5D-3L 评分之间没有相关性。
PGI 可能会捕捉到肯尼亚感染艾滋病毒的孕妇生活中与通用工具不同的社会和情感方面的情况。突出对患者 HRQoL 重要的领域是关键，因为重点转向第四个 90，这也可能为符合患者需求的护理计划的设计提供信息。
