Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK.
Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
Sci Rep. 2022 Mar 9;12(1):2803. doi: 10.1038/s41598-022-06579-9.
The COVID-19 pandemic has demonstrated the real need for mechanisms to control the spread of airborne respiratory pathogens. Thus, preventing the spread of disease from pathogens has come to the forefront of the public consciousness. This has brought an increasing demand for novel technologies to prioritise clean air. In this study we report on the efficacy of novel biocide treated filters and their antimicrobial activity against bacteria, fungi and viruses. The antimicrobial filters reported here are shown to kill pathogens, such as Candida albicans, Escherichia coli and MRSA in under 15 min and to destroy SARS-CoV-2 viral particles in under 30 s following contact with the filter. Through air flow rate testing, light microscopy and SEM, the filters are shown to maintain their structure and filtration function. Further to this, the filters are shown to be extremely durable and to maintain antimicrobial activity throughout the operational lifetime of the product. Lastly, the filters have been tested in field trials onboard the UK rail network, showing excellent efficacy in reducing the burden of microbial species colonising the air conditioning system.
COVID-19 大流行表明,我们确实需要控制空气传播呼吸道病原体的传播的机制。因此,防止病原体传播已成为公众意识的重中之重。这对优先考虑清洁空气的新技术提出了越来越高的要求。在本研究中,我们报告了新型杀生物剂处理过的过滤器的功效及其对细菌、真菌和病毒的抗菌活性。这里报道的抗菌过滤器在与过滤器接触不到 15 分钟内就能杀死病原体,如白色念珠菌、大肠杆菌和耐甲氧西林金黄色葡萄球菌,并且在 30 秒内就能杀死 SARS-CoV-2 病毒颗粒。通过空气流速测试、光学显微镜和扫描电子显微镜,这些过滤器显示出它们能够保持结构和过滤功能。此外,这些过滤器极其耐用,并且在产品的整个运行寿命内都保持抗菌活性。最后,这些过滤器已经在英国铁路网络上进行了现场试验,结果表明它们在减少空调系统中微生物定植负担方面非常有效。