Schwartz C J, Valente A J, Sprague E A, Kelley J L, Suenram C A, Graves D T, Rozek M M, Edwards E H, Delgado R
Semin Thromb Hemost. 1986 Apr;12(2):79-86. doi: 10.1055/s-2007-1003539.
This article has addressed the roles of the monocyte-macrophage in atherogenesis and factors influencing monocyte recruitment to the intima. The diversity of the secretory products of the macrophage and their putative participatory roles in pathogenesis have been reviewed and discussed. Additionally, we have presented summary data on the monocyte chemoattractant peptide SMC-CF and on the differentiation of the monocyte-derived foam cell. Discussion has centered on the concept of atherosclerosis as an inflammatory process.
本文探讨了单核细胞-巨噬细胞在动脉粥样硬化形成中的作用以及影响单核细胞向内膜募集的因素。对巨噬细胞分泌产物的多样性及其在发病机制中的假定参与作用进行了综述和讨论。此外，我们还给出了关于单核细胞趋化因子SMC-CF以及单核细胞源性泡沫细胞分化的汇总数据。讨论集中在动脉粥样硬化是一种炎症过程的概念上。
