Huang Jin, Zhao Dandan, Cui Chaojing, Hao Jianxiong, Zhang Zhentao, Guo Limin
College of Food Science & Biology, Hebei University of Science & Technology, Shijiazhuang 051432, China.
Technical Institute of Physics and Chemistry CAS, Beijing 100190, China.
Foods. 2022 Mar 7;11(5):769. doi: 10.3390/foods11050769.
Phenylethanoid glycosides (PhGs) are obtained from a wide range of sources and show strong biological and pharmacological activities, such as antioxidant, antibacterial and neuroprotective effects. However, intestinal malabsorption and the low bioavailability of PhGs seriously affect their application. Delivery systems are an effective method to improve the bioavailability of active substances. Scope and approach: In this article, the biological activities of and delivery systems for PhGs are introduced. The application statuses of delivery systems for echinacoside, acteoside and salidroside are reviewed. Finally, the problems of the lack of uniform standards for delivery systems and the poor targeted delivery accuracy of PhGs in the current research are proposed and suggestions for future research are put forward based on those problems.
Although there are still some problems in the delivery system of phenylethanoside, such as inconsistent standards and inaccurate delivery, phenylethanoside itself has been proven to have a variety of physiological activities. Therefore, the action mechanism and application of phenylethanoside and its delivery system should be studied further.
苯乙醇苷（PhGs）来源广泛，具有强大的生物学和药理活性，如抗氧化、抗菌和神经保护作用。然而，PhGs的肠道吸收不良和低生物利用度严重影响其应用。递送系统是提高活性物质生物利用度的有效方法。
本文介绍了PhGs的生物学活性及其递送系统。综述了紫锥菊苷、毛蕊花糖苷和红景天苷递送系统的应用现状。最后，指出了当前研究中递送系统缺乏统一标准以及PhGs靶向递送准确性差的问题，并基于这些问题对未来研究提出了建议。
尽管苯乙醇苷递送系统仍存在一些问题，如标准不一致和递送不准确，但苯乙醇苷本身已被证明具有多种生理活性。因此，应进一步研究苯乙醇苷及其递送系统的作用机制和应用。
