Allergic Unit, Department of Pediatric, Meyer Children's Hospital, 50139 Florence, Italy.
Allergy Unit, CHU de Montpellier, Université de Montpellier, 34295 Montpellier, France.
Nutrients. 2022 Feb 26;14(5):998. doi: 10.3390/nu14050998.
Peach allergy is emerging as a common type of fresh-fruit allergy in Europe, especially in the Mediterranean area. The clinical manifestations of peach allergy tend to have a peculiar geographical distribution and can range from mild oral symptoms to anaphylaxis, depending on the allergic sensitization profile. The peach allergen Pru p 7, also known as peamaclein, has recently been identified as a marker of peach allergy severity and as being responsible for peculiar clinical features in areas with high exposure to cypress pollen. This review addresses the latest findings on molecular allergens for the diagnosis of peach allergy, the clinical phenotypes and endotypes of peach allergy in adults and children, and management strategies, including immunotherapy, for peach allergy.
桃过敏在欧洲逐渐成为一种常见的鲜果过敏，尤其是在地中海地区。桃过敏的临床表现具有独特的地域分布，根据过敏致敏谱，可从轻度口腔症状到过敏反应不等。桃过敏原 Pru p 7，也称为桃皮素，最近被确定为桃过敏严重程度的标志物，并负责在高接触柏花粉的地区引起特殊的临床特征。这篇综述介绍了用于诊断桃过敏的分子过敏原的最新发现，成人和儿童桃过敏的临床表型和内型，以及桃过敏的管理策略，包括免疫疗法。
