慢性肾衰竭与心血管疾病：综合评估
Chronic Renal Failure and Cardiovascular Disease: A Comprehensive Appraisal.
作者信息
Skalsky Keren, Shiyovich Arthur, Steinmetz Tali, Kornowski Ran
机构信息
Department of Cardiology, Rabin Medical Center, Petah Tikva 4941492, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.
出版信息
J Clin Med. 2022 Feb 28;11(5):1335. doi: 10.3390/jcm11051335.
Abstract
Coronary artery disease is highly prevalent in patients with chronic kidney disease. The concomitant renal disease often poses a major challenge in decision making as symptoms, cardiac biomarkers and noninvasive studies for evaluation of myocardial ischemia have different sensitivity and specificity thresholds in this specific population. Moreover, the effectiveness and safety of intervention and medical treatment in those patients is of great doubt as most clinical studies exclude patients with advance CKD. In the present paper, we discuss and review the literature in the diagnosis, treatment and prevention of CAD in the acute and chronic setting, in patients with CKD.
摘要
冠状动脉疾病在慢性肾脏病患者中非常普遍。伴随的肾脏疾病在决策过程中常常构成重大挑战，因为在这一特定人群中，用于评估心肌缺血的症状、心脏生物标志物和非侵入性检查具有不同的敏感性和特异性阈值。此外，由于大多数临床研究将晚期慢性肾脏病患者排除在外，这些患者干预和治疗的有效性及安全性备受质疑。在本文中，我们讨论并回顾了有关慢性肾脏病患者急慢性情况下冠心病诊断、治疗及预防的文献。
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