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使用双镜系统观察近视成年人的远距观看对调节反应和瞳孔大小的影响。

Effects of Extended Viewing Distance on Accommodative Response and Pupil Size of Myopic Adults by Using a Double-Mirror System.

机构信息

Ph.D. Program in Medical Biotechnology, National Chung Hsing University, Taichung 402, Taiwan.

Department of Optometry, Chung Shan Medical University, Taichung 402, Taiwan.

出版信息

Int J Environ Res Public Health. 2022 Mar 3;19(5):2942. doi: 10.3390/ijerph19052942.

Abstract

Purposes: This study discussed the accommodative response and pupil size of myopic adults using a double-mirror system (DMS). The viewing distance could be extended to 2.285 m by using a DMS, which resulted in a reduction and increase in the accommodative response and pupil size, respectively. By using a DMS, the reduction of the accommodative response could improve eye fatigue with near work. Method: Sixty subjects aged between 18 and 22 years old were recruited in this study, and the average age was 20.67 ± 1.09. There were two main steps in the experimental process. In the first step, we examined the subjects’ refraction state and visual function, and then fitted disposable contact lenses with a corresponding refractive error. In the second step, the subjects gazed at an object from a viewing distance of 0.4 m and at a virtual image through a DMS, respectively, and the accommodative response and pupil size were measured using an open field autorefractor. Results: When the subjects gazed at the object from a distance of 0.4 m, or gazed at the virtual image through a DMS, the mean value of the accommodative response was 1.74 ± 0.43 or 0.16 ± 0.47 D, and the pupil size was 3.98 ± 0.06 mm or 4.18 ± 0.58 mm, respectively. With an increase in the viewing distance from 0.4 m to 2.285 m, the accommodative response and pupil size were significantly reduced about 1.58 D and enlarged about 0.2 mm, respectively. For three asterisk targets of different sizes (1 cm × 1 cm, 2 cm × 2 cm, and 3 cm × 3 cm), the mean accommodative response and pupil size through the DMS was 0.19 ± 0.16, 0.27 ± 0.24, 0.26 ± 0.19 D; and 4.20 ± 1.02, 3.94 ± 0.73, 4.21 ± 0.57 mm, respectively. The changes of the accommodative response and pupil size were not significant with the size of the targets (p > 0.05). In the low or high myopia group, the accommodative response of 0.4 m and 2.285 m was 1.68 ± 0.42 D and 0.21 ± 0.48 D; and 1.88 ± 0.25 D and 0.05 ± 0.40 D, respectively. The accommodative response was significantly reduced by 1.47 D and 1.83 D for these two groups. The accommodative microfluctuations (AMFs) were stable when a DMS was used; on the contrary, the AMFs were unstable at a viewing distance of 0.4 m. Conclusions: In this study, the imaging through a DMS extended the viewing distance and enlarged the image, and resulted in a reduction in the accommodative response and an increase in the pupil size. For the low myopia group and the high myopia group, the accommodative response and pupil size were statistically significantly different before and after the use of the DMS. The reduction of the accommodative response could be applied for the improvement of asthenopia.

摘要

目的

本研究使用双像镜系统(DMS)探讨了近视成年人的调节反应和瞳孔大小。通过使用 DMS,可以将观看距离延长至 2.285 米,从而分别减少和增加调节反应和瞳孔大小。通过使用 DMS,可以减少近用工作时的调节疲劳。方法:本研究共招募了 60 名年龄在 18 至 22 岁之间的受试者,平均年龄为 20.67±1.09 岁。实验过程有两个主要步骤。在第一步中,我们检查了受试者的屈光度和视觉功能,然后用相应的屈光不正来适配一次性隐形眼镜。在第二步中,受试者分别从 0.4 米的距离注视物体,通过 DMS 注视虚拟图像,并使用开放式自动屈光仪测量调节反应和瞳孔大小。结果:当受试者从 0.4 米的距离注视物体,或通过 DMS 注视虚拟图像时,调节反应的平均值分别为 1.74±0.43 或 0.16±0.47 D,瞳孔大小分别为 3.98±0.06 毫米或 4.18±0.58 毫米。随着观看距离从 0.4 米增加到 2.285 米,调节反应和瞳孔大小分别显著减少了约 1.58 D 和扩大了约 0.2 毫米。对于三个不同大小(1cm×1cm、2cm×2cm 和 3cm×3cm)的星标目标,通过 DMS 的平均调节反应和瞳孔大小分别为 0.19±0.16、0.27±0.24、0.26±0.19 D;和 4.20±1.02、3.94±0.73、4.21±0.57 毫米。目标大小的变化对调节反应和瞳孔大小没有显著影响(p>0.05)。在低度近视组和高度近视组中,0.4 米和 2.285 米的调节反应分别为 1.68±0.42 D 和 0.21±0.48 D;和 1.88±0.25 D 和 0.05±0.40 D。两组的调节反应分别显著减少了 1.47 D 和 1.83 D。使用 DMS 时,调节微波动(AMFs)稳定;相反,在 0.4 米的观看距离时,AMFs 不稳定。结论:在这项研究中,通过 DMS 的成像扩展了观看距离并放大了图像,从而减少了调节反应并增加了瞳孔大小。对于低度近视组和高度近视组,使用 DMS 前后调节反应和瞳孔大小有统计学差异。调节反应的减少可用于改善视疲劳。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b04/8910498/64bb42dce3f2/ijerph-19-02942-g001.jpg

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