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静脉注射联合玻璃体内注射促红细胞生成素治疗甲醇中毒性视神经病变:一例报告及简要综述

Intravenous plus intravitreal erythropoietin for management of methanol toxicity optic neuropathy: A case report and brief review.

作者信息

Rashidi Alavijeh Mehran, Mazaheri-Tehrani Sadegh, Saffari Amir Sepehr, Fazel Mohammadreza, Fazel Farhad

机构信息

Student Research Committee, School of Medicine Isfahan University of Medical Sciences Isfahan Iran.

Isfahan Eye Research Center, Department of Ophthalmology Isfahan University of Medical Sciences Isfahan Iran.

出版信息

Clin Case Rep. 2023 Mar 2;11(3):e7011. doi: 10.1002/ccr3.7011. eCollection 2023 Mar.

Abstract

Methanol can inhibit cellular aerobic respiration pathway and causes cell hypoxia specially in optic neurons. Despite using many drugs, methanol-induced optic neuropathy (MION) still has a poor prognosis. Here we present a case of MION which is managed by a combination of intravenous and intravitreal erythropoietin in addition to corticosteroids.

摘要

甲醇可抑制细胞有氧呼吸途径,尤其对视神经细胞造成缺氧。尽管使用了多种药物,但甲醇所致视神经病变(MION)的预后仍然很差。在此,我们报告一例MION病例,该病例除使用皮质类固醇外,还联合静脉和玻璃体内注射促红细胞生成素进行治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7673/9979964/d350647d35ef/CCR3-11-e7011-g001.jpg

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