咖啡因摄入及其对健康活跃成年人运动后心率变异性恢复的影响：一项系统综述和荟萃分析。
Caffeine intake and its influences on heart rate variability recovery in healthy active adults after exercise: A systematic review and meta-analysis.
作者信息
Porto Andrey Alves, Benjamim Cicero Jonas R, Gonzaga Luana Almeida, Luciano de Almeida Mariana, Bueno Júnior Carlos Roberto, Garner David M, Valenti Vitor Engrácia
机构信息
Department of Physical Therapy, Faculty of Sciences and Technologies, UNESP, Presidente Prudente, Brazil; Autonomic Nervous System Center, UNESP, Marilia, SP, Brazil.
Department of Internal Medicine, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirão Preto, Brazil.
出版信息
Nutr Metab Cardiovasc Dis. 2022 May;32(5):1071-1082. doi: 10.1016/j.numecd.2022.01.015. Epub 2022 Jan 22.
AIMS
Results regarding the effects of caffeine (CAF) intake on the autonomic control of heart rate recovery exercise remain inconclusive. Thus far, no study has used effect measures to pool the results of different experiments. We aim to assess the acute effect of CAF intake before exercise on the recovery of heart rate variability (HRV) after exercise through a systematic review and meta-analysis.
DATA SYNTHESIS
Randomized controlled clinical trials were included; sample composed of physically active or trained adults; CAF should be offered/ingested before exercise, with dosage between 100 and 400 mg or between 2 and 6 mg/kg and administration/ingestion route analogous in the protocols; studies required to present results of HRV indices before and after exercise. Bias risk analysis and meta-analysis were performed. Twelve studies were included in the qualitative synthesis and five studies were encompassed in the quantitative synthesis (meta-analysis). For the Root-mean-square standard deviation (RMSSD) index we revealed p = 0.67, Total 95% confidence interval (95% CI) ranged from -0.45 to 0.29, and 66.7% for heterogeneity between groups were reported. Concerning the High Frequency (HF) index, we observed p = 0.22, Total 95% CI that ranged from -0.34 to 0.30, and 44% for heterogeneity between groups.
CONCLUSIONS
CAF intake did not affect heart rate variability recovery after exercise.
目的
关于摄入咖啡因（CAF）对运动后心率恢复自主控制的影响，研究结果尚无定论。迄今为止，尚无研究采用效应量来汇总不同实验的结果。我们旨在通过系统评价和荟萃分析，评估运动前摄入CAF对运动后心率变异性（HRV）恢复的急性影响。
数据综合
纳入随机对照临床试验；样本由身体活跃或经过训练的成年人组成；CAF应在运动前提供/摄入，剂量在100至400毫克之间或2至6毫克/千克之间，且在方案中的给药/摄入途径类似；研究需呈现运动前后HRV指标的结果。进行了偏倚风险分析和荟萃分析。定性综合纳入了12项研究，定量综合（荟萃分析）涵盖了5项研究。对于均方根标准差（RMSSD）指数，我们发现p = 0.67，总体95%置信区间（95%CI）为-0.45至0.29，组间异质性为66.7%。关于高频（HF）指数，我们观察到p = 0.22，总体95%CI为-0.34至0.30，组间异质性为44%。
结论
摄入CAF不影响运动后心率变异性的恢复。
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