Nijland Leontien M G, van Veen Ruben N, Vanhommerig Joost W, Hermsen Brenda B J, van Rutte Pim W J, de Castro Steve M M
Department of Surgery, OLVG Hospital, Amsterdam, The Netherlands.
Department of Research and Epidemiology, OLVG Hospital, Amsterdam, The Netherlands.
Surg Obes Relat Dis. 2022 May;18(5):634-640. doi: 10.1016/j.soard.2022.01.018. Epub 2022 Feb 1.
Approximately 80% of the patients undergoing bariatric surgery are female, with half of them undergoing surgery during their reproductive years. Most guidelines recommend that women wait at least 12 months after surgery before becoming pregnant. No previous studies have investigated whether becoming pregnant in the first or second year after surgery affects weight loss.
The aim of this study was to assess whether pregnancy within the first or second year after bariatric surgery affects weight loss up to 5 years after surgery.
A single institution.
This study is a retrospective study of women who underwent primary bariatric surgery between 2012 and 2016. Weight outcomes were measured until 5 years after surgery. A linear mixed model was used to assess the effect of the time between surgery and conception in groups on the basis of percentage total weight loss.
A total of 55 patients undergoing a primary bariatric procedure were included. Forty-seven women underwent a laparoscopic Roux-en-Y gastric bypass (85.5%), and 8 underwent a sleeve gastrectomy (14.5%). The median time between surgery and estimated conception was 22 months (range: 0-51 months). Women who became pregnant between 12 and 24 months after bariatric surgery (n = 18) and women who became pregnant after 24 months (n = 24) had significantly more weight (β = 3.95, P = .020, and β = 4.09, P =.024, respectively) than women who became pregnant within 12 months after bariatric surgery (n = 12).
Our results suggest that pregnancy within 12 months after bariatric surgery negatively affects the long-term weight loss after bariatric surgery.
接受减肥手术的患者中约80%为女性，其中一半在生育年龄接受手术。大多数指南建议女性在手术后至少等待12个月再怀孕。此前尚无研究调查术后第一年或第二年怀孕是否会影响体重减轻。
本研究的目的是评估减肥手术后第一年或第二年怀孕是否会影响术后5年内的体重减轻情况。
单一机构。
本研究是一项对2012年至2016年间接受初次减肥手术的女性进行的回顾性研究。测量术后5年的体重结果。使用线性混合模型根据总体重减轻百分比评估各组手术与受孕之间的时间对体重的影响。
共纳入55例接受初次减肥手术的患者。47例女性接受了腹腔镜Roux-en-Y胃旁路手术（85.5%），8例接受了袖状胃切除术（14.5%）。手术与估计受孕之间的中位时间为22个月（范围：0至51个月）。减肥手术后12至24个月怀孕的女性（n = 18）和24个月后怀孕的女性（n = 24）的体重明显高于减肥手术后12个月内怀孕的女性（n = 12）（β分别为3.95，P = 0.020和β = 4.09，P = 0.024）。
我们的结果表明，减肥手术后12个月内怀孕会对减肥手术后的长期体重减轻产生负面影响。
