Jain Deeptee, Kelly Michael P, Gornet Matthew F, Kenneth Burkus J, Hodges Scott D, Dryer Randall F, McConnell Jeffrey R, Lanman Todd H, Daniel Riew K
Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, MO, USA
Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Int J Spine Surg. 2022 Feb;16(1):95-101. doi: 10.14444/8199. Epub 2022 Mar 10.
Driving an automobile requires the ability to turn the neck laterally. Anecdotally, patients with multilevel fusions often complain about restricted turning motion. The purpose of this study was to compare the effectiveness of cervical disc arthroplasty (CDA) with anterior cervical discectomy and fusion (ACDF) on driving disability improvement at 10-year follow-up after a 2-level procedure.
In the original randomized controlled trial, patients with cervical radiculopathy or myelopathy at 2 levels underwent CDA or ACDF. The driving disability question from the Neck Disability Index was rated from 0 to 5 years preoperatively and up to 10 years postoperatively. Severity of driving disability was categorized into "none" (score 0), "mild" (1 or 2), and "severe" (3, 4, or 5). Score and severity were compared between groups.
Out of 397 patients, 148 CDA and 118 ACDF patients had 10-year follow-up. Driving disability scores were not different between the groups preoperatively (CDA: 2.65; ACDF: 2.71, = 0.699). Postoperatively, the scores in the CDA group were significantly lower than those in the ACDF group at 5 (0.60 vs 1.08, ≤ 0.001) and 10 years (0.66 vs 1.07, = 0.001). Mean score improvement in the CDA group was significantly greater than the ACDF group at 10-year follow-up (-1.94 vs -1.63, = 0.003). The majority of patients reported severe driving disability (CDA: 56.9%, ACDF: 58.0%, = 0.968) before surgery. After surgery, a greater proportion of patients in the CDA group had neck pain-free driving compared with the ACDF group at 5 (63.3% vs 41.8%, < 0.001) and 10 years (61.8% vs 41.2%, = 0.003).
In patients with cervical radiculopathy/myelopathy and 2-level disease, CDA provided greater improvements in driving disability as compared with ACDF at 10-year follow-up. This is the first report of its kind. This finding may be attributable to preservation of motion associated with CDA.
This study provides valuable information regarding the improvement of driving disability after both CDA and ACDF. It demonstrates that both procedures result in significant improvements, with CDA resulting in even better improvements than ACDF, up to 10 year follow-up.
驾驶汽车需要能够向侧面转动颈部。据传闻,接受多节段融合手术的患者经常抱怨颈部转动受限。本研究的目的是比较颈椎间盘置换术(CDA)与颈椎前路椎间盘切除融合术(ACDF)在两级手术10年随访时对改善驾驶功能障碍的效果。
在最初的随机对照试验中,患有两节段神经根型颈椎病或脊髓型颈椎病的患者接受了CDA或ACDF手术。颈部功能障碍指数中的驾驶功能障碍问题在术前0至5年以及术后长达10年进行评分。驾驶功能障碍的严重程度分为“无”(评分为0)、“轻度”(1或2)和“重度”(3、4或5)。对两组之间的评分和严重程度进行比较。
在397例患者中,148例接受CDA手术和118例接受ACDF手术的患者进行了10年随访。术前两组的驾驶功能障碍评分无差异(CDA组:2.65;ACDF组:2.71,P = 0.699)。术后,CDA组在5年(0.60对1.08,P≤0.001)和10年(0.66对1.07,P = 0.001)时的评分显著低于ACDF组。在10年随访时,CDA组的平均评分改善显著大于ACDF组(-1.94对-1.63,P = 0.003)。大多数患者在手术前报告有严重的驾驶功能障碍(CDA组:56.9%,ACDF组:58.0%,P = 0.968)。手术后,与ACDF组相比,CDA组在5年(63.3%对41.8%,P<0.001)和10年(61.8%对41.2%,P = 0.003)时有更大比例的患者在驾驶时无颈部疼痛。
在患有神经根型颈椎病/脊髓型颈椎病和两节段疾病的患者中,在10年随访时,与ACDF相比,CDA在改善驾驶功能障碍方面有更大的改善。这是同类研究中的首次报告。这一发现可能归因于CDA保留了运动功能。
本研究提供了关于CDA和ACDF术后改善驾驶功能障碍的有价值信息。它表明两种手术都能带来显著改善,在长达10年的随访中,CDA的改善效果甚至优于ACDF。