Department of Community Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Students' Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
Eur J Clin Nutr. 2022 Sep;76(9):1315-1322. doi: 10.1038/s41430-022-01108-3. Epub 2022 Mar 10.
The irregular meal pattern and meal-skipping might be related to irritable bowel syndrome (IBS), however, findings of previous investigations are contradictory. We aimed to examine the relation of meal regularity with IBS in Iranian adult population.
Data on 4599 adults who worked in 50 different health centers were used in this cross-sectional study. Dietary habits were measured using a pretested questionnaire. IBS identification was performed through the use of a modified version of Rome III questionnaire.
IBS was prevalent among 18.6% of men and 24.1% of women. After adjustment for potential confounders, those with regular meal pattern, in comparison to those with irregular meals, had 40% lower odds for IBS (OR:0.60, 95%CI: 0.41-0.87). Individuals with regular meals had also 82 lower risk for IBS-Mixed, in comparison to those who had irregular meals (OR:0.18, 0.95%CI: 0.08-0.43). Stratified analysis by gender revealed that women with regular meals, compared with those who did not, had 44% lower risk for IBS (OR: 0.56, 0.95%CI: 0.34-0.91). Normal-weight individuals who had regular meal pattern, compared to those who did not, had 63% lower risks for IBS (OR:0.37, 95%CI: 0.22-0.64). Furthermore, subjects who had regular meal pattern had 53% lower risk for severe symptoms of IBS (OR:0.47, 95%CI: 0.30-0.71).
We found that participants with regular meal pattern had reduced odds of IBS, IBS-Mixed and the syndrome severity. Meal regularity was also linked to reduced IBS prevalence in women, and in normal-weight individuals. More prospective studies are needed to affirm these associations.
不规律的进餐模式和漏餐可能与肠易激综合征（IBS）有关，但先前的研究结果存在矛盾。我们旨在研究伊朗成年人群中进餐规律与 IBS 的关系。
本横断面研究使用了来自 50 个不同健康中心的 4599 名成年人的数据。饮食情况通过预先测试的问卷进行测量。通过使用罗马 III 问卷的修改版来确定 IBS 的存在。
男性中 IBS 的患病率为 18.6%，女性中为 24.1%。调整潜在混杂因素后，与进餐不规律的人相比，进餐规律的人患 IBS 的可能性降低 40%（OR：0.60，95%CI：0.41-0.87）。与进餐不规律的人相比，进餐规律的人患 IBS-Mixed 的风险也降低了 82%（OR：0.18，95%CI：0.08-0.43）。按性别进行分层分析显示，与不规律进餐的女性相比，规律进餐的女性患 IBS 的风险降低了 44%（OR：0.56，95%CI：0.34-0.91）。与不规律进餐的人相比，规律进餐的正常体重个体患 IBS 的风险降低了 63%（OR：0.37，95%CI：0.22-0.64）。此外，规律进餐的人患 IBS 严重症状的风险降低了 53%（OR：0.47，95%CI：0.30-0.71）。
我们发现，进餐规律的人患 IBS、IBS-Mixed 和该综合征严重程度的几率降低。进餐规律与女性和正常体重人群中 IBS 患病率降低有关。需要更多的前瞻性研究来证实这些关联。
