Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.
Eur J Clin Nutr. 2018 Nov;72(11):1537-1547. doi: 10.1038/s41430-018-0109-y. Epub 2018 Mar 13.
BACKGROUND/OBJECTIVES: The associations between empirically derived dietary habits and irritable bowel syndrome (IBS) have not been investigated. This study aimed to assess the relationship between empirically derived dietary habits and IBS in a large population of Iranian adults.
SUBJECTS/METHODS: In a cross-sectional study, dietary habits of 4763 adults were assessed in three domains, "meal pattern", "eating rate" and "intra-meal fluid intake". We used latent class analysis to identify classes of dietary habits. IBS was defined based on ROME III criteria.
IBS was prevalent in 20.3% (n = 966) of the study population. Two distinct classes of meal patterns: "regular" and "irregular", three classes of eating rates: "moderate", "moderate-to-slow" and "moderate-to-fast" and two classes of fluid ingestion with meals: "moderate" and "heavy intra-meal drinking" were identified. After adjustment for confounders, "heavy intra-meal fluid intake" was protectively associated with IBS (OR = 0.79; 95% CI:0.64-0.96). When potential confounders were considered, "meal pattern" and "eating rate" were not significantly associated with IBS in the whole population. After adjustment for confounders, women with "irregular meal pattern" had a 30% greater risk of having IBS, compared with those with "regular meal pattern" (OR = 1.30; 95% CI:1.02-1.67). Overweight participants with "fast eating rate" were 70% more likely to have IBS, compared to those with "moderate eating rate" (OR = 1.70; 95% CI:1.13-2.55). "Irregular meal pattern" was related to frequency and severity of abdominal pain.
We found a significant association between heavy intra-meal fluid intake" and IBS. More large-scale prospective studies are needed to affirm this association.
背景/目的：实证得出的饮食习惯与肠易激综合征（IBS）之间的关联尚未得到研究。本研究旨在评估伊朗成年人中实证得出的饮食习惯与 IBS 之间的关系。
受试者/方法：在一项横断面研究中，评估了 4763 名成年人在三个领域的饮食习惯，即“进餐模式”、“进食速度”和“进餐时液体摄入”。我们使用潜在类别分析来确定饮食习惯类别。IBS 根据罗马 III 标准定义。
研究人群中 IBS 的患病率为 20.3%（n=966）。两种不同的进餐模式：“规律”和“不规律”，三种进食速度类别：“中等”、“中等至缓慢”和“中等至快速”，以及两种进餐时液体摄入类别：“中等”和“大量进餐饮用”。调整混杂因素后，“大量进餐饮用”与 IBS 呈保护性相关（OR=0.79；95%CI：0.64-0.96）。当考虑潜在混杂因素时，“进餐模式”和“进食速度”在整个人群中与 IBS 无显著相关性。调整混杂因素后，与“规律进餐模式”相比，“不规律进餐模式”的女性发生 IBS 的风险增加 30%（OR=1.30；95%CI：1.02-1.67）。与“中等进食速度”相比，“快速进食速度”的超重参与者发生 IBS 的可能性增加 70%（OR=1.70；95%CI：1.13-2.55）。“不规律进餐模式”与腹痛的频率和严重程度有关。
我们发现“大量进餐饮用”与 IBS 之间存在显著关联。需要更多的大规模前瞻性研究来证实这一关联。
