Li Hou-Kun, Du Jin-Peng, Huang Da-Geng, Shan Le-Qun, He Bao-Rong, Yan Liang, Zhao Qing-Peng, Hao Ding-Jun
Xi'an Jiaotong University No. 25 Zhuquan Road, Xi'an 710054, Shaanxi, China.
Am J Transl Res. 2022 Feb 15;14(2):909-917. eCollection 2022.
To analyze the surgical treatment of patients with cervical brucellosis with osteoporosis over a 4-year period in Northwest China.
From 2013 to 2018, 22 patients (12 males and 10 females) with lower cervical spine brucellosis (C3-C7) underwent anterior lesion debridement, decompression, bone grafting and internal fixation combined with posterior bone graft fusion and internal fixation (ADDF+PIF). The follow-up period averaged 37.4 months (ranging from 24 to 57 months).
Involvement of 1 vertebra was observed in 3 patients, involvement of 3 vertebrae was observed in 9 patients, and involvement of 3 vertebrae was observed in 10 patients. Before surgery, 1 patient had Frankel grade B, 2 had grade C, 9 had grade D, and 10 had grade E. In the final follow-up, 12 patients had neurological deficits, 10 patients improved by one grade, 6 patients improved by two grades, and the neurological status of 6 patients remained unchanged. In all cases, it was observed that bone fusion required 6.8 months on average. The kyphosis Cobb angle was enhanced from an average of 11.5° preoperatively (range 0°-24°) to 0.13° postoperatively (range 1°-5°), and there was no vital loss of correction in the follow-up.
ADDF+PIF is an effective and safe treatment for patients with lower cervical brucellosis with osteoporosis.
分析中国西北地区4年间骨质疏松性颈椎布鲁氏菌病患者的外科治疗情况。
2013年至2018年，22例下颈椎布鲁氏菌病（C3-C7）患者（男12例，女10例）接受了前路病灶清除、减压、植骨融合内固定联合后路植骨融合内固定术（ADDF+PIF）。随访期平均为37.4个月（24至57个月）。
3例患者累及1个椎体，9例患者累及3个椎体，10例患者累及3个椎体。术前，1例患者为Frankel B级，2例为C级，9例为D级，10例为E级。末次随访时，12例患者存在神经功能缺损，10例患者神经功能改善1级，6例患者改善2级，6例患者神经功能无变化。所有病例中，平均骨融合时间为6.8个月。后凸Cobb角从术前平均1并随访中矫正度无显著丢失。
ADDF+PIF是治疗骨质疏松性下颈椎布鲁氏菌病患者的一种有效且安全的方法。 5°（范围0°-24°）增加至术后0.13°（范围1°-5°），
