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大脑状况介导了衰老和幸福感之间的关联。

Brain conditions mediate the association between aging and happiness.

机构信息

Open Innovation Institute, Kyoto University, Kyoto, Japan.

Smart-Aging Research Center, Tohoku University, Sendai, Japan.

出版信息

Sci Rep. 2022 Mar 11;12(1):4290. doi: 10.1038/s41598-022-07748-6.

DOI:10.1038/s41598-022-07748-6
PMID:35277535
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8915763/
Abstract

As the population ages, the realization of a long and happy life is becoming an increasingly important issue in many societies. Therefore, it is important to clarify how happiness and the brain change with aging. In this study, which was conducted with 417 healthy adults in Japan, the analysis showed that fractional anisotropy (FA) correlated with happiness, especially in the internal capsule, corona radiata, posterior thalamic radiation, cingulum, and superior longitudinal fasciculus. According to previous neuroscience studies, these regions are involved in emotional regulation. In psychological studies, emotional regulation has been associated with improvement in happiness. Therefore, this study is the first to show that FA mediates the relationship between age and subjective happiness in a way that bridges these different fields.

摘要

随着人口老龄化,在许多社会中,实现长寿和幸福的生活正变得越来越重要。因此,阐明幸福和大脑如何随年龄变化非常重要。在这项在日本对 417 名健康成年人进行的研究中,分析表明,分数各向异性(FA)与幸福感相关,尤其是在内囊、辐射冠、后丘脑辐射、扣带和上纵束。根据以前的神经科学研究,这些区域参与情绪调节。在心理学研究中,情绪调节与幸福感的提高有关。因此,这项研究首次表明,FA 以一种连接这些不同领域的方式,调节年龄与主观幸福感之间的关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a7/8917153/e971fb5ffecd/41598_2022_7748_Fig8_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a7/8917153/f8dad7c721c8/41598_2022_7748_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a7/8917153/3c29d2ecf43d/41598_2022_7748_Fig2_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a7/8917153/85fa9fb7a6d9/41598_2022_7748_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a7/8917153/5a4bc16e5253/41598_2022_7748_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a7/8917153/1f6d7c710a55/41598_2022_7748_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a7/8917153/c6c7cbeaf8d7/41598_2022_7748_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a7/8917153/e971fb5ffecd/41598_2022_7748_Fig8_HTML.jpg

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