Stricker Nikki H, Stricker John L, Karstens Aimee J, Geske Jennifer R, Fields Julie A, Hassenstab Jason, Schwarz Christopher G, Tosakulwong Nirubol, Wiste Heather J, Jack Clifford R, Kantarci Kejal, Mielke Michelle M
Department of Psychiatry and Psychology Mayo Clinic Rochester Minnesota USA.
Department of Information Technology Mayo Clinic Rochester Minnesota USA.
Alzheimers Dement (Amst). 2022 Mar 9;14(1):e12299. doi: 10.1002/dad2.12299. eCollection 2022.
This study established the psychometric properties and preliminary validity of the Stricker Learning Span (SLS), a novel computer adaptive word list memory test designed for remote assessment and optimized for smartphone use.
Women enrolled in the Mayo Clinic Specialized Center of Research Excellence (SCORE) were recruited via e-mail or phone to complete two remote cognitive testing sessions. Convergent validity was assessed through correlation with previously administered in-person neuropsychological tests (n = 96, ages 55-79) and criterion validity through associations with magnetic resonance imaging measures of neurodegeneration sensitive to Alzheimer's disease (n = 47).
SLS performance significantly correlated with the Auditory Verbal Learning Test and measures of neurodegeneration (temporal meta-regions of interest and entorhinal cortical thickness, adjusting for age and education). Test-retest reliabilities across two sessions were 0.71-0.76 (two-way mixed intraclass correlation coefficients).
The SLS is a valid and reliable self-administered memory test that shows promise for remote assessment of aging and neurodegenerative disorders.
本研究确定了斯特里克学习广度（SLS）的心理测量特性和初步效度，这是一种专为远程评估设计并针对智能手机使用进行优化的新型计算机自适应单词列表记忆测试。
通过电子邮件或电话招募参加梅奥诊所卓越研究专业中心（SCORE）的女性，以完成两次远程认知测试。通过与先前进行的面对面神经心理学测试（n = 96，年龄55 - 79岁）的相关性评估收敛效度，并通过与对阿尔茨海默病敏感的神经退行性变的磁共振成像测量的关联评估标准效度（n = 47）。
SLS表现与听觉词语学习测试和神经退行性变测量（感兴趣的颞叶元区域和内嗅皮质厚度，校正年龄和教育程度）显著相关。两次测试之间的重测信度为0.71 - 0.76（双向混合组内相关系数）。
SLS是一种有效且可靠的自我管理记忆测试，对衰老和神经退行性疾病的远程评估具有前景。
