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新冠病毒病后累及下颌骨的毛霉菌病:一例报告并简要回顾文献

Post coronavirus disease mucormycosis involving the mandible: A case report with brief note on literature.

作者信息

Bhanumurthy Lokesh, Krishna P Sai, Sekhar Prasanna, Makesh Raj L S

机构信息

Department of Oral Pathology, Tagore Dental College and Hospital, Chennai, Tamil Nadu, India.

出版信息

J Oral Maxillofac Pathol. 2021 Sep-Dec;25(3):407-410. doi: 10.4103/jomfp.jomfp_355_21. Epub 2022 Jan 11.

DOI:10.4103/jomfp.jomfp_355_21
PMID:35281175
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8859598/
Abstract

Mucormycosis also termed as phycomycosis or zygomycosis is less commonly seen in oral cavity. However, it is an invasive, life-threatening and aggressive fungal infection. It mostly targets individuals with altered immunological system and diabetes. In this recent pandemic situation, the individuals affected with coronavirus disease 2019 (COVID-19) are also affected with this fungal infection which commonly involves the maxilla. In this case report, we present a case of a 45-year-old female affected with mucormycosis in post-COVID scenario involving mandible which is quite rare situation. The case report covers clinical findings, radiographic investigations and histopathological details with brief on literature review. Since mucormycosis is aggressive fungal infection, it should be handled with multimodal approach to reduce the systemic damage of an individual, morbidity and mortality.

摘要

毛霉菌病也被称为藻菌病或接合菌病,在口腔中较少见。然而,它是一种侵袭性、危及生命且具有侵袭性的真菌感染。它主要针对免疫系统改变和患有糖尿病的个体。在当前这种大流行情况下,感染2019冠状病毒病(COVID-19)的个体也会感染这种真菌感染,且通常累及上颌骨。在本病例报告中,我们呈现了一例45岁女性在COVID后出现累及下颌骨的毛霉菌病病例,这是一种相当罕见的情况。该病例报告涵盖了临床发现、影像学检查和组织病理学细节,并简要进行了文献综述。由于毛霉菌病是侵袭性真菌感染,应采用多模式方法进行处理,以减少个体的全身损害、发病率和死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d586/8859598/df6015889ae2/JOMFP-25-407-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d586/8859598/56c7f727a3a9/JOMFP-25-407-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d586/8859598/77755a6096f5/JOMFP-25-407-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d586/8859598/df6015889ae2/JOMFP-25-407-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d586/8859598/56c7f727a3a9/JOMFP-25-407-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d586/8859598/77755a6096f5/JOMFP-25-407-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d586/8859598/df6015889ae2/JOMFP-25-407-g003.jpg

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