Nair Lekshmy S R, Soman Anandaraj, George Sageena, Jose Deepak, Sain Shaniya, Salim Shiad
Department of Pediatric and Preventive Dentistry, PMS College of Dental Science and Research, Trivandrum, Kerala, India.
Department of Oral and Maxillofacial Surgery, PMS College of Dental Science and Research, Trivandrum, Kerala, India.
J Int Soc Prev Community Dent. 2022 Jan 29;12(1):85-92. doi: 10.4103/jispcd.JISPCD_245_21. eCollection 2022 Jan-Feb.
The aim of this study was to evaluate the efficacy of 0.2% chlorhexidine and 4% tulsi extract as toothbrush decontaminants.
Of 100 children, who attended the outpatient unit of Department of Pediatric dentistry, 81 children, who satisfied all the inclusion criteria were subjected to systematic sampling, after arranging them in the alphabetical order and were grouped into three. The first child came under Group I, second under Group II, third under Group III, fourth one again under Group I, and so on till the 81st child. In the baseline phase, the children were provided precoded toothbrushes and toothpastes and instructed to place those brushes to be put after use, in single-use glasses. After obtaining the baseline value of colony count, the participants of Group I was given 0.2% chlorhexidine, Group II was given 4% tulsi extract, and distilled water for Group III, to be used as toothbrush decontaminants for 5 days. The toothbrushes were then collected back, and were subjected to microbial analysis. Statistical analysis was performed by using Kruskal-Wallis one-way analysis of variance (ANOVA) and Mann-Whitney test with < 0.05.
All test solutions, 0.2% chlorhexidine and 4% tulsi extract, except for distilled water, showed a statistically significant reduction of count. There was no statistical difference between the efficacies of 4% tulsi extract and 0.2% chlorhexidine, although the latter showed a better reduction.
Tulsi extract may well be a perfect replacement to chlorhexidine for reducing the count in the child toothbrushes.
本研究旨在评估0.2%洗必泰溶液和4%罗勒提取物作为牙刷消毒剂的效果。
在小儿牙科门诊就诊的100名儿童中，81名符合所有纳入标准的儿童按字母顺序排列后进行系统抽样，并分为三组。第一个孩子归入第一组，第二个归入第二组，第三个归入第三组，第四个再次归入第一组，依此类推，直到第81个孩子。在基线阶段，为孩子们提供预先编码的牙刷和牙膏，并指导他们将使用后的牙刷放在一次性杯子里。在获得菌落计数的基线值后，第一组参与者使用0.2%洗必泰溶液，第二组使用4%罗勒提取物，第三组使用蒸馏水作为牙刷消毒剂，为期5天。然后将牙刷收回并进行微生物分析。采用Kruskal-Wallis单因素方差分析和Mann-Whitney检验进行统计分析，P<0.05为有统计学意义。
除蒸馏水外，所有测试溶液，即0.2%洗必泰溶液和4%罗勒提取物，均显示菌落计数有统计学意义的减少。4%罗勒提取物和0.2%洗必泰溶液的效果之间没有统计学差异，尽管后者的减少效果更好。
罗勒提取物很可能是洗必泰的理想替代品，可用于减少儿童牙刷上的菌落计数。
