Zarogoulidis Paul, Huang Haidong, Chen Wei, Petridis Dimitris, Matthaios Dimitris, Hohenforst-Schmidt Wolfgang, Tolis Christos, Tsakiridis Kosmas, Baka Sofia, Arnaoutoglou Christos, Saroglou Maria, Tryfon Stavros, Ioannidis Aris, Freitag Lutz, Kosmidis Christoforos, Bai Chong
3rd Department of Surgery, "AHEPA" University Hospital, Aristotle University of Thessaloniki, Medical School, Thessaloniki, Greece.
Pulmonary Oncology Department, "Bioclinic" Private Hospital, Thessaloniki, Greece.
J Cancer. 2022 Jan 31;13(4):1307-1312. doi: 10.7150/jca.67113. eCollection 2022.
Endoscopic techniques have been upgraded in the recent 10 years. We can use the radial endobronchial ultrasound to reach distal nodules in the periphery of the lungs, but also we can use it in order to make biopsies in lesions without endobronchial findings. We included in our study 248 patients with pulmonary nodules up to 4 cm. We use a radial endobronchial system from FUJI, a PENTAX bronchoscope and a C-ARM. We recorded the cancer type, biopsy method, time of each procedure, cell blocks and slices from cell blocks. Two thirds of patients belonged to males (61.7%), forceps was the main tissue extraction technique (118, 47.6%) and tumors sized 1 to 2 cm were the most encountered (96, 38.7%). Samples with tissue content were present in 175 patients (70.6%) and one cell block dominated in the samples (109, 43.9%). Less than 20 minutes were needed to complete the operative procedure for the half patients (127, 51.2%), the C-Arm implementation concerned 117 persons (47.2%) and the majority of tumors was located in the central area of the lungs (178, 71.8%). Less time was necessary for central lesions and larger biopsy samples were acquired without the extensive use of C-ARM. The larger the nodule ≥2cm and in periphery the less we use the C-ARM and the time of the procedure is between 20-40 minutes. Moreover; we have more tissue sample and cell block slices.
内镜技术在最近10年里得到了升级。我们可以使用径向支气管内超声抵达肺外周的远端结节,也可以用它对没有支气管内表现的病变进行活检。我们的研究纳入了248例肺结节直径达4厘米的患者。我们使用了富士的径向支气管内系统、宾得支气管镜和C形臂。我们记录了癌症类型、活检方法、每个操作的时间、细胞块以及细胞块切片。三分之二的患者为男性(61.7%),钳取是主要的组织提取技术(118例,47.6%),1至2厘米大小的肿瘤最为常见(96例,38.7%)。175例患者(70.6%)的样本含有组织成分,且样本中一个细胞块占主导(109例,43.9%)。半数患者(共127例,51.2%)完成手术操作所需时间不到20分钟,117人(47.2%)使用了C形臂,大多数肿瘤位于肺中央区域(178例,71.8%)。中央病变所需时间较短,无需大量使用C形臂就能获取更大的活检样本。结节≥2厘米且位于外周时,C形臂的使用越少,操作时间在20至40分钟之间。此外,我们获得了更多的组织样本和细胞块切片。