中药治疗心力衰竭的机制与疗效
Mechanisms and Efficacy of Traditional Chinese Medicine in Heart Failure.
作者信息
Wang Anzhu, Zhao Wei, Yan Kaituo, Huang Pingping, Zhang Hongwei, Zhang Zhibo, Zhang Dawu, Ma Xiaochang
机构信息
Graduate School, China Academy of Chinese Medical Sciences, Beijing, China.
Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
出版信息
Front Pharmacol. 2022 Feb 24;13:810587. doi: 10.3389/fphar.2022.810587. eCollection 2022.
Abstract
Heart failure (HF) is one of the main public health problems at present. Although some breakthroughs have been made in the treatment of HF, the mortality rate remains very high. However, we should also pay attention to improving the quality of life of patients with HF. Traditional Chinese medicine (TCM) has a long history of being used to treat HF. To demonstrate the clinical effects and mechanisms of TCM, we searched published clinical trial studies and basic studies. The search results showed that adjuvant therapy with TCM might benefit patients with HF, and its mechanism may be related to microvascular circulation, myocardial energy metabolism, oxidative stress, and inflammation.
摘要
心力衰竭（HF）是当前主要的公共卫生问题之一。尽管在HF治疗方面已取得一些突破，但死亡率仍然很高。然而，我们也应注重提高HF患者的生活质量。中医治疗HF有着悠久的历史。为了阐明中医的临床疗效及作用机制，我们检索了已发表的临床试验研究和基础研究。检索结果表明，中医辅助治疗可能使HF患者获益，其机制可能与微循环、心肌能量代谢、氧化应激及炎症有关。
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